DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr6 and Jaml

DIOPT Version :9

Sequence 1:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_006510445.4	Gene:	Jaml / 270152	MGIID:	2685484	Length:	405	Species:	Mus musculus

Alignment Length:	371	Identity:	85/371 - (22%)
Similarity:	143/371 - (38%)	Gaps:	94/371 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LPTAPTAAYTHPKWMEPYFDPSTPRNVTALMGKSAYLSCRVRNLANK---TVSWIRHRD-----I 113
            |.|...|...:|:.: |....|:|: :...:|:|..:.|.|:....|   .|.|:..:|     .
Mouse    35 LGTVILAPVGYPQGL-PGLTVSSPQ-LRVHVGESVLMGCVVQRTEEKHVDRVDWLFSKDKDDASE 97

  Fly   114 HILTVGSYTYTSDQRFQATHH--QDT--EDWTLQIKWAQKRDAGMYECQI--------STQPVRS 166
            ::|...|.......|||...|  .||  .|.:|.::..||.|.|:|.|:|        ..:||..
Mouse    98 YVLFYYSNLSVPTGRFQNRSHLVGDTFHNDGSLLLQDVQKADEGIYTCEIRLKNESMVMKKPVEL 162

  Fly   167 YFVRLNVVVPTATILGGPDLHVDKGSTINLTCTVKFSPEP-PAYIFWY-----HHEE--VINYDS 223
            :      |:|...    .||.|..|.|..:.|:::.:.|. ...:.|.     |.||  |::|||
Mouse   163 W------VLPEEP----KDLRVRVGDTTQMRCSIQSTEEKRVTKVNWMFSSGSHTEEETVLSYDS 217

  Fly   224 S-RGGV--------SVITEKGDVTTS--FLLIQNADLADSGKYSCAPSNADVASVRVHVLNV--- 274
            : |.|.        :.:...||::.:  .:.:|....:|.|.|:|:.....:.|.:..||:|
Mouse   218 NMRSGKFQSLGRFRNRVDLTGDISRNDGSIKLQTVKESDQGIYTCSIYVGKLESRKTIVLHVVQD 282

  Fly   275 --RAIISGEHPEAMQTGSSGCQYNWLTIVLLLGLVLCYSSQQCSSAVPASLTSSLPLPSQLPLPA 337
              :..||...|  ...|..|. .|...:|:::|:|       |::.              |.||.
Mouse   283 EFQRTISPTPP--TDKGQQGI-LNGNQLVIIVGIV-------CATF--------------LLLPV 323

  Fly   338 AAAATTTATGESASSESVTAARA--------------SAATTTTTT 369
            .......|....:|..|:.:.::              |:.||..||
Mouse   324 LILIVKKAKWNKSSVSSMASVKSLENKEKINPEKHIYSSITTWETT 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	28/114 (25%)
		IG_like	80..175	CDD:214653	28/114 (25%)
		IG_like	184..271	CDD:214653	25/105 (24%)
		IGc2	191..262	CDD:197706	21/89 (24%)
Jaml	XP_006510445.4	V-set	55..165	CDD:369466	29/116 (25%)
Jaml	XP_006510445.4	V-set	167..280	CDD:369466	27/116 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	42	1.000	Inparanoid score	I5499
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050