DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr6 and Ncam1

DIOPT Version :9

Sequence 1:NP_001287018.1 Gene:dpr6 / 50296 FlyBaseID:FBgn0040823 Length:396 Species:Drosophila melanogaster
Sequence 2:XP_038936733.1 Gene:Ncam1 / 24586 RGDID:67378 Length:1136 Species:Rattus norvegicus


Alignment Length:270 Identity:59/270 - (21%)
Similarity:93/270 - (34%) Gaps:76/270 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    88 GKSAYLSCRVRNLANKTVSWIRH--RDIHILTVGSYTYTSDQRFQATHHQDTEDWTLQIKWAQKR 150
            |:.|.:.|.|.:....|:.| :|  ||:.:        ..|.||....:.     .|||:..:|.
  Rat   132 GEDAVIVCDVVSSLPPTIIW-KHKGRDVIL--------KKDVRFIVLSNN-----YLQIRGIKKT 182

  Fly   151 DAGMYECQ-----------------ISTQPVRSYFVRLNVVVPTATILGGPDLHVDKGSTINLTC 198
            |.|.|.|:                 ::..|  :...|.::|..||.:          |.::.|.|
  Rat   183 DEGTYRCEG
RILARGEINFKDIQVIVNVPP--TVQARQSIVNATANL----------GQSVTLVC 235

  Fly   199 TVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNADLADSGKYSCAPSN-- 261
            .....|||.  :.|....|.|..:.......:.::    .:|.|.|:|.|..|..:|.|...|  
  Rat   236 DADGFPEPT--MSWTKDGEPIENEEEDDEKHIFSD----DSSELTIRNVDKNDEAEYVCIAENKA 294

  Fly   262 -ADVASVRVHVLNVRAIISGEHPEAMQ-----------TGSSGCQYNWLTIVLLLGLVLCYSSQQ 314
             ...||:.:.|.....|...|:..||:           :|.......|.|           |::.
  Rat   295 GEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRT-----------STRN 348

  Fly   315 CSSAVPASLT 324
            .||...||.|
  Rat   349 ISSEEKASWT 358

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr6NP_001287018.1 V-set 79..174 CDD:284989 22/104 (21%)
IG_like 80..175 CDD:214653 22/105 (21%)
IG_like 184..271 CDD:214653 20/89 (22%)
IGc2 191..262 CDD:197706 18/73 (25%)
Ncam1XP_038936733.1 IgI_1_NCAM-1 20..116 CDD:409451
Ig strand B 37..41 CDD:409451
Ig strand C 51..55 CDD:409451
Ig strand E 79..83 CDD:409451
Ig strand F 93..98 CDD:409451
Ig strand G 107..110 CDD:409451
IG_like 124..190 CDD:214653 19/71 (27%)
Ig strand B 135..139 CDD:409353 1/3 (33%)
Ig strand C 148..152 CDD:409353 2/4 (50%)
Ig strand E 172..176 CDD:409353 1/8 (13%)
Ig strand F 186..191 CDD:409353 2/4 (50%)
IgI_3_NCAM-1 211..308 CDD:143207 26/114 (23%)
Ig strand B 231..235 CDD:143207 1/3 (33%)
Ig strand C 244..248 CDD:143207 0/5 (0%)
Ig strand E 271..275 CDD:143207 2/3 (67%)
Ig strand F 285..290 CDD:143207 2/4 (50%)
Ig strand G 298..301 CDD:143207 1/2 (50%)
IgI_NCAM-1 307..413 CDD:143277 13/63 (21%)
Ig strand B 326..330 CDD:143277 0/3 (0%)
Ig strand C 339..343 CDD:143277 0/3 (0%)
Ig strand E 379..383 CDD:143277
Ig strand F 393..398 CDD:143277
Ig strand G 406..409 CDD:143277
Ig_3 422..494 CDD:404760
Ig strand B 433..437 CDD:409353
Ig strand C 446..450 CDD:409353
Ig strand E 473..477 CDD:409353
Ig strand F 487..492 CDD:409353
FN3 509..606 CDD:238020
fn3 619..701 CDD:394996
Herpes_BLLF1 <842..1133 CDD:282904
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.