DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr6 and Kirrel2

DIOPT Version :9

Sequence 1:NP_001287018.1 Gene:dpr6 / 50296 FlyBaseID:FBgn0040823 Length:396 Species:Drosophila melanogaster
Sequence 2:NP_766486.1 Gene:Kirrel2 / 243911 MGIID:2442334 Length:700 Species:Mus musculus


Alignment Length:339 Identity:77/339 - (22%)
Similarity:115/339 - (33%) Gaps:84/339 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    73 PYFDPSTPRNVTALMGKSAYLSCRV---RNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHH 134
            |:| ...|.::..|:|:.|.|.|.:   |.|    |.|.:..    |.:|.             .
Mouse    21 PHF-LQQPEDMVVLLGEEARLPCALGAYRGL----VQWTKDG----LALGG-------------E 63

  Fly   135 QDTEDWT--------------LQIKWAQKRDAGMYECQISTQPVRSYFVRLNVVVP--TATILGG 183
            :|...|:              |.||..:..|...||||.|...:||...:|:|:||  ...:|||
Mouse    64 RDLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQASQAGLRSRPAQLHVMVPPEAPQVLGG 128

  Fly   184 PDLHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNAD 248
            |.:.:..|...||||..:....|...:.|:  .:.|..|.|....:.:.:|...|....|.....
Mouse   129 PSVSLVAGVPGNLTCRSRGDSRPAPELLWF--RDGIRLDGSSFHQTTLKDKATGTVENTLFLTPS 191

  Fly   249 LADSG-------KYSCAPSNADVASVRVHVLNVRAIISGEHPEAMQTGSSG---CQ--------- 294
            ..|.|       :....|:..|.| |.:.:.....:.....|:.:|.|...   ||         
Mouse   192 SHDDGATLICRARSQALPTGRDTA-VTLSLQYPPMVTLSAEPQTVQEGEKVTFLCQATAQPPVTG 255

  Fly   295 YNW--------------LTIV----LLLGLVLCYSSQQCSSAVPASLTSSLPLPSQLPLPAAAAA 341
            |.|              |.:|    .|...|.|..|....||..::....|..|.   |.|...:
Mouse   256 YRWAKGGSPVLGARGPRLEVVADATFLTEPVSCEVSNAVGSANRSTALEVLYGPI---LQAKPKS 317

  Fly   342 TTTATGESASSESV 355
            .:...|:.||...|
Mouse   318 VSVDVGKDASFSCV 331

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr6NP_001287018.1 V-set 79..174 CDD:284989 26/111 (23%)
IG_like 80..175 CDD:214653 27/111 (24%)
IG_like 184..271 CDD:214653 20/93 (22%)
IGc2 191..262 CDD:197706 16/77 (21%)
Kirrel2NP_766486.1 IG 27..116 CDD:214652 26/109 (24%)
Ig 122..220 CDD:416386 23/100 (23%)
Ig strand A 123..126 CDD:409353 0/2 (0%)
Ig strand A' 129..133 CDD:409353 1/3 (33%)
Ig strand B 140..147 CDD:409353 4/6 (67%)
Cell attachment site. /evidence=ECO:0000255 146..148 0/1 (0%)
Ig strand C 153..158 CDD:409353 0/4 (0%)
Ig strand C' 161..163 CDD:409353 0/1 (0%)
Ig strand D 166..173 CDD:409353 1/6 (17%)
Ig strand E 180..188 CDD:409353 2/7 (29%)
Ig strand F 197..205 CDD:409353 0/7 (0%)
Ig strand G 211..217 CDD:409353 2/6 (33%)
Ig_3 223..292 CDD:404760 12/68 (18%)
Ig strand B 241..245 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 1/3 (33%)
Ig strand E 272..275 CDD:409353 1/2 (50%)
Ig strand F 281..290 CDD:409353 3/8 (38%)
Ig strand G 298..301 CDD:409353 0/2 (0%)
Ig 315..392 CDD:416386 4/17 (24%)
Ig strand A' 316..321 CDD:409353 0/4 (0%)
Ig strand B 324..333 CDD:409353 3/8 (38%)
Ig strand C 339..343 CDD:409353
Ig strand C' 346..348 CDD:409353
Ig strand D 351..354 CDD:409353
Ig strand E 355..360 CDD:409353
Ig strand F 368..376 CDD:409353
Ig strand G 382..392 CDD:409353
Ig 394..498 CDD:416386
Ig strand A 395..399 CDD:409353
Ig strand A' 401..404 CDD:409353
Ig strand B 412..419 CDD:409353
Ig strand C 426..431 CDD:409353
Ig strand C' 433..436 CDD:409353
Ig strand D 444..451 CDD:409353
Ig strand E 461..468 CDD:409353
Ig strand F 479..486 CDD:409353
Ig strand G 489..496 CDD:409353
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..576
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 671..700
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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