DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr6 and Ntm

DIOPT Version :9

Sequence 1:NP_001287018.1 Gene:dpr6 / 50296 FlyBaseID:FBgn0040823 Length:396 Species:Drosophila melanogaster
Sequence 2:NP_001344522.1 Gene:Ntm / 235106 MGIID:2446259 Length:367 Species:Mus musculus


Alignment Length:297 Identity:83/297 - (27%)
Similarity:122/297 - (41%) Gaps:65/297 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 YNSLDDLLTTTPTPGQAALLL----PTAPTAAYTHPKWMEPYFDPSTPRNVTALMGKSAYLSCRV 97
            :||:...:.|    |.|||.|    |.....| |.||.|:         |||...|:||.|.|.:
Mouse     9 HNSISWAIFT----GLAALCLFQGVPVRSGDA-TFPKAMD---------NVTVRQGESATLRCTI 59

  Fly    98 RNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQDTEDWTLQIKWAQKRDAGMYECQIST- 161
            .|...: |:|:....  ||..|:..:..|.|.....:..|: ::::|:.....|.|.|.|.:.| 
Mouse    60 DNRVTR-VAWLNRST--ILYAGNDKWCLDPRVVLLSNTQTQ-YSIEIQNVDVYDEGPYTCSVQTD 120

  Fly   162 -QPVRSYFVRLNVVVPTATILGGPDLHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSR 225
             .|..|. |.|.|.|....:....|:.:::|:.|:|||.....|||.  :.|.|        .|.
Mouse   121 NHPKTSR-VHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPT--VTWRH--------ISP 174

  Fly   226 GGVSVITEKGDVTTSFLLIQNADLADSGKYSCAPSNADVASV---RVHV-LNVRAIISGEHPEAM 286
            ..|..::|     ..:|.||......||:|.|:.|| |||:.   ||.| :|....||......:
Mouse   175 KAVGFVSE-----DEYLEIQGITREQSGEYECSASN-DVAAPVVRRVKVTVNYPPYISEAKGTGV 233

  Fly   287 QTGSSGCQYNWLTIVLLLGLVLCYSSQQC-SSAVPAS 322
            ..|..|                   :.|| :||||::
Mouse   234 PVGQKG-------------------TLQCEASAVPSA 251

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr6NP_001287018.1 V-set 79..174 CDD:284989 27/96 (28%)
IG_like 80..175 CDD:214653 28/96 (29%)
IG_like 184..271 CDD:214653 28/89 (31%)
IGc2 191..262 CDD:197706 21/70 (30%)
NtmNP_001344522.1 Ig 44..132 CDD:416386 27/92 (29%)
Ig strand A' 44..49 CDD:409353 3/4 (75%)
Ig strand B 51..59 CDD:409353 4/7 (57%)
CDR1 59..63 CDD:409353 1/3 (33%)
FR2 64..70 CDD:409353 2/6 (33%)
Ig strand C 64..70 CDD:409353 2/6 (33%)
CDR2 71..83 CDD:409353 3/13 (23%)
Ig strand C' 72..76 CDD:409353 1/5 (20%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 8/34 (24%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 0/6 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 4/9 (44%)
FR4 125..132 CDD:409353 3/7 (43%)
Ig_3 136..205 CDD:404760 21/83 (25%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 4/8 (50%)
Ig strand F 197..205 CDD:409353 3/7 (43%)
Ig_3 222..299 CDD:404760 10/49 (20%)
putative Ig strand A 223..229 CDD:409353 2/5 (40%)
Ig strand B 239..243 CDD:409353 1/22 (5%)
Ig strand C 252..256 CDD:409353 83/297 (28%)
Ig strand E 278..282 CDD:409353
Ig strand F 292..297 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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