DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr6 and rig-5

DIOPT Version :9

Sequence 1:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001251131.1	Gene:	rig-5 / 172791	WormBaseID:	WBGene00004372	Length:	482	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	52/208 - (25%)
Similarity:	84/208 - (40%)	Gaps:	40/208 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 PYFDPSTPRNVTALMGKSAYLSCRVRNLANKTVSWI----------------RHRDIHILTVGSY 121
            |.....:..:..||:|:....:|.|.:|.:..|:::                |.|:
Worm    84 PTIQQPSMSSAVALLGQDVDFTCIVNDLGSHMVAFVKADSPPRLLSFDEKVFRRRN--------- 139

  Fly   122 TYTSDQRFQATHHQDTEDWTLQIKWAQKRDAGMYECQISTQPVRSYFVRLNVVVPTATILGGP-D 185
            .|....|....|:    :|.|.||..|:.|.|.|.|||:|:|:......|:|.||.......| .
Worm   140 KYELKPRIGDLHN----EWVLTIKNVQESDRGNYSCQINTEPITLSTGELDVKVPPVVSRSTPAA 200

  Fly   186 LHVDKGSTINLTCTVKFSPEPPAYIFWYHHE-EVINYDSSRG-GVSVITEKGDVTTSFLLIQNAD 248
            :.|.:|:.::|||....:|.|.  :.|...: ::|.|:.:.| |.||.  .|.|    |.:....
Worm   201 VEVREGNNVSLTCKADGNPTPT--VIWRRQDRQIIRYNGATGFGASVF--HGPV----LHLTKVS 257

  Fly   249 LADSGKYSCAPSN 261
            .....:|.|..||
Worm   258 RKHMSEYLCVASN 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	26/110 (24%)
		IG_like	80..175	CDD:214653	27/110 (25%)
		IG_like	184..271	CDD:214653	22/81 (27%)
		IGc2	191..262	CDD:197706	20/73 (27%)
rig-5	NP_001251131.1	IG_like	92..189	CDD:214653	27/109 (25%)
		Ig_3	191..270	CDD:372822	20/86 (23%)
		IG	294..380	CDD:214652
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910