DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr6 and Dscam

DIOPT Version :9

Sequence 1:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_006522949.1	Gene:	Dscam / 13508	MGIID:	1196281	Length:	2034	Species:	Mus musculus

Alignment Length:	209	Identity:	54/209 - (25%)
Similarity:	87/209 - (41%)	Gaps:	37/209 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 TPRNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQDTEDWTLQ 143
            :||.|.:.:|....|||.|....::.:||.|:.:  ||..|     .:.|....:|.:     |.
Mouse   319 SPRKVKSSVGSQVSLSCSVTGNEDQELSWYRNGE--ILNPG-----KNVRITGLNHAN-----LI 371

  Fly   144 IKWAQKRDAGMYECQISTQPVRSYFVR---------LNVVVPTAT---ILGGPDLHVDKGSTINL 196
            :....|.|.|.|:|          |||         :.||:...|   |....:..|.....::|
Mouse   372 MDHMVKSDGGAYQC----------FVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSL 426

  Fly   197 TCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNADLADSGKYSCAPSN 261
            .|.||.:|.|.  :.|...::.|...|......:||.:|:| .|:|.|.::.:.|.|.|.|..:|
Mouse   427 VCNVKGTPLPT--VTWTLDDDPILKGSGHRISQMITSEGNV-VSYLNISSSQVRDGGVYRCTANN 488

  Fly   262 ADVASVRVHVLNVR 275
            :....:....:|||
Mouse   489 SAGVVLYQARINVR 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	25/103 (24%)
		IG_like	80..175	CDD:214653	26/103 (25%)
		IG_like	184..271	CDD:214653	22/86 (26%)
		IGc2	191..262	CDD:197706	20/70 (29%)
Dscam	XP_006522949.1	Ig	15..115	CDD:386229
		IGc2	239..300	CDD:197706
		IG	320..400	CDD:214652	25/101 (25%)
		Ig_3	410..488	CDD:372822	22/80 (28%)
		IGc2	518..575	CDD:197706
		Ig	596..686	CDD:386229
		Ig_DSCAM	707..784	CDD:143211
		Ig	802..889	CDD:386229
		FN3	885..978	CDD:238020
		FN3	986..1083	CDD:238020
		FN3	1091..1184	CDD:238020
		FN3	1189..1278	CDD:238020
		Ig_3	1301..1363	CDD:372822
		FN3	1380..1470	CDD:238020
		FN3	1486..1555	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900