Protein Alignment dpr6 and negr1

DIOPT Version :10

• Sequence 1: NP_001287018.1
• Gene: dpr6 / 50296
• FlyBaseID: FBgn0040823
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: XP_031755650.1
• Gene: negr1 / 100127726
• XenbaseID: XB-GENE-987949
• Length: 388
• Species: Xenopus tropicalis
• Alignment Length: 378
• Identity: 87/378 - (23%)
• Similarity: 140/378 - (37%)
• Gaps: 91/378 - (24%)

  Fly    56 LLPTA-PTAAYTHPKWMEPYFDPSTPRNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVG 119
            |||:. |.......:|  |..|     |:....|::|.|.|.:...|:|. :|:....  |:..|
 Frog    28 LLPSCLPAGQSMDFQW--PAVD-----NLVVRQGETAMLRCFLEEGASKG-AWLNRSS--IIFAG 82

  Fly   120 SYTYTSDQRFQ-ATHHQDTEDWTLQIKWAQKRDAGMYECQISTQ-PVRSYFVRLNVVVPTATILG 182
            ...::.|.|.. ||  ...::::|:|:.....|.|.|.|.:.|: ..|:..|.|.|.|.......
 Frog    83 GDKWSVDPRVSIAT--SSKQEYSLRIQKVDVSDDGPYTCSVQTEHSPRTLQVHLTVHVSPKIYDI 145

  Fly   183 GPDLHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNA 247
            ..|:.|::|:.::|.|.....|||.  |.|.|    |:..:.:.|          :..:|.|...
 Frog   146 SSDMTVNEGTNVSLICLATGKPEPS--ISWRH----ISPSAKQFG----------SGQYLDIYGI 194

  Fly   248 DLADSGKYSCAPSN----ADVASVRVHVLNVRAIISGEHPEAMQTGSSG---CQ----------- 294
            ....:|.|.|:..|    .||..|:|.| |....|....|..:..|.:|   |:
 Frog   195 TRDQAGDYECSAENDVSFPDVKKVKVTV-NFAPTILEITPTGVSLGRTGLIRCETAAVPAPVFEW 258

  Fly   295 ------------------YNWLTIVLL-------LGLVLCYSSQQCSSAVPASLTSSLPLPSQLP 334
                              ||..:|:.:       .|...|.:..:..::     .:|||| :|:.
 Frog   259 YKGEKKLTNGQRGIRIQNYNTRSILTVSNVTEEHFGNYTCVAVNKLGTS-----NASLPL-NQII 317

  Fly   335 LPAAAAATTTATGESASSESVTAARAS------AATTTTTTATRKRCPAVKSC 381
            .|    :||:....||.......||:|      ||.:|.......|...:.||
 Frog   318 EP----STTSPVTSSAKYSVKHYARSSSDKPHYAAPSTAQYGITGRAEILFSC 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	FR1	79..96	CDD:409355	4/16 (25%)
		IG_like	80..175	CDD:214653	25/96 (26%)
		Ig strand A'	83..85	CDD:409355	0/1 (0%)
		Ig strand B	89..97	CDD:409355	3/7 (43%)
		CDR1	97..104	CDD:409355	1/6 (17%)
		FR2	105..114	CDD:409355	1/8 (13%)
		Ig strand C	105..110	CDD:409355	1/4 (25%)
		CDR2	115..129	CDD:409355	3/13 (23%)
		Ig strand D	129..135	CDD:409355	2/6 (33%)
		FR3	130..159	CDD:409355	8/29 (28%)
		Ig strand E	139..145	CDD:409355	1/5 (20%)
		Ig strand F	153..160	CDD:409355	3/6 (50%)
		IG_like	184..271	CDD:214653	23/90 (26%)
		Ig strand B	194..198	CDD:409353	1/3 (33%)
		Ig strand C	209..213	CDD:409353	1/3 (33%)
		Ig strand E	240..244	CDD:409353	1/3 (33%)
		Ig strand F	254..259	CDD:409353	2/4 (50%)
		Ig strand G	268..271	CDD:409353	1/2 (50%)
negr1	XP_031755650.1	Ig	44..136	CDD:472250	26/101 (26%)
		Ig strand B	57..61	CDD:409353	2/3 (67%)
		Ig strand C	70..73	CDD:409353	0/3 (0%)
		Ig strand E	102..106	CDD:409353	1/3 (33%)
		Ig strand F	116..121	CDD:409353	2/4 (50%)
		Ig strand G	129..132	CDD:409353	0/2 (0%)
		Ig	146..222	CDD:472250	23/91 (25%)
		Ig strand B	157..161	CDD:409301	1/3 (33%)
		Ig strand C	170..174	CDD:409301	1/5 (20%)
		Ig strand E	187..191	CDD:409301	1/3 (33%)
		Ig strand F	201..206	CDD:409301	2/4 (50%)
		Ig strand G	215..218	CDD:409301	1/2 (50%)
		Ig_3	226..302	CDD:464046	10/75 (13%)