DRSC/TRiP Functional Genomics Resources

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Protein Alignment P2RY1 and AstC-R2

DIOPT Version :9

Sequence 1:NP_002554.1 Gene:P2RY1 / 5028 HGNCID:8539 Length:373 Species:Homo sapiens
Sequence 2:NP_001303398.1 Gene:AstC-R2 / 40019 FlyBaseID:FBgn0036789 Length:593 Species:Drosophila melanogaster


Alignment Length:325 Identity:86/325 - (26%)
Similarity:154/325 - (47%) Gaps:37/325 - (11%)


- Green bases have known domain annotations that are detailed below.


Human    57 VYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGD 121
            :|.||.|||..||::.|::.:...|..:..::|:.|||:||..:::.:|.|: |.....:|.||:
  Fly   151 LYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFLL-YTMQVGNWPFGN 214

Human   122 AMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKS-------LGRLKKKNAICISVLVWLIV 179
            .|||.......:..:.|.:||..:||.||..|.:|:.|       :.:|       :|...|:..
  Fly   215 YMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKL-------VSAFAWMTS 272

Human   180 VVAISPILFYSGTGVRKNKTITCY----DTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI 240
            |:.:.|::.::.|....|..::|.    ||.:.....::.:||:   |..|..||..||..|.|:
  Fly   273 VLLMLPVILFASTVQSSNGNVSCNIEWPDTQNSHTDSTFILYSL---VLGFATPLTFILVFYCLV 334

Human   241 VRAL-----IYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND 300
            :|.|     .:|..:.....||...||:.|::.:...::|..:.     :..|....|..||...
  Fly   335 IRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWIS-----QVALISSAPQRCASRL 394

Human   301 RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEF 365
            .: |.:.....|:..||.::||||....|.|::...:|...|:|: :.|.|.:.|:   :..|:|
  Fly   395 EL-AVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTCAARK-DVNAQLQLEN---SFFPKF 454

Human   366  365
              Fly   455  454

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
P2RY1NP_002554.1 7tmA_P2Y1 52..335 CDD:320499 78/293 (27%)
TM helix 1 52..79 CDD:320499 9/21 (43%)
TM helix 2 86..111 CDD:320499 8/24 (33%)
TM helix 3 124..154 CDD:320499 9/29 (31%)
TM helix 4 166..188 CDD:320499 4/21 (19%)
TM helix 5 214..243 CDD:320499 10/28 (36%)
TM helix 6 253..283 CDD:320499 6/29 (21%)
TM helix 7 303..328 CDD:320499 8/24 (33%)
AstC-R2NP_001303398.1 7tm_4 156..>372 CDD:304433 60/226 (27%)
7tm_1 162..417 CDD:278431 68/271 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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