Protein Alignment Atg10 and ATG10

DIOPT Version :9

• Sequence 1: NP_001097215.1
• Gene: Atg10 / 50253
• FlyBaseID: FBgn0040780
• Length: 172
• Species: Drosophila melanogaster
• Sequence 2: NP_001124500.1
• Gene: ATG10 / 83734
• HGNCID: 20315
• Length: 220
• Species: Homo sapiens
• Alignment Length: 210
• Identity: 57/210 - (27%)
• Similarity: 93/210 - (44%)
• Gaps: 62/210 - (29%)

  Fly     7 KDFLSQAKQFLEISQKLGDNWILEQKDSNEPNTYLKCSQKIKCRGGKDNS--------------- 56
            |.|.....:|::.||::||:|  |.:.|.:.:....|....:.:.|...|
Human    10 KTFQRYCAEFIKHSQQIGDSW--EWRPSKDCSDGYMCKIHFQIKNGSVMSHLGASTHGQTCLPME 72

  Fly    57 ------------------AELVSVEYHVVFSVSYQVPMLFFQAHRSDGSLLDVEATWRMFMPESK 103
                              :|::..||||::|.|||||:|:|:|...||..|.::..|
Human    73 EAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIW-------- 129

  Fly   104 ASDLHQ------------ILTQMDHPVLFRPFMALHPCRTAE----VLKQFGK--PSCNQVLTFI 150
             ..:|:            .:||.:||:|.:||..||||:|.|    |||...|  .:.|.:.:::
Human   130 -EGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWL 193

  Fly   151 SLYGPHVQLHLQNAY 165
            |:.||.|.|:|..:|
Human   194 SIVGPVVGLNLPLSY 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg10	NP_001097215.1	Autophagy_act_C	66..130	CDD:281917	25/75 (33%)
ATG10	NP_001124500.1	Autophagy_act_C	100..167	CDD:309203	25/75 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11549
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I5242
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1538225at2759
OrthoFinder	1	1.000	-	-		FOG0005851
OrthoInspector	1	1.000	-	-		oto90025
orthoMCL	1	0.900	-	-		OOG6_104820
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3745
SonicParanoid	1	1.000	-	-		X6351
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.900