DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg10 and Atg10

DIOPT Version :9

Sequence 1:	NP_001097215.1	Gene:	Atg10 / 50253	FlyBaseID:	FBgn0040780	Length:	172	Species:	Drosophila melanogaster
Sequence 2:	NP_080046.3	Gene:	Atg10 / 66795	MGIID:	1914045	Length:	211	Species:	Mus musculus

Alignment Length:	206	Identity:	60/206 - (29%)
Similarity:	93/206 - (45%)	Gaps:	58/206 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KDFLSQAKQFLEISQKLGDNWILEQKDSNEPNTYLKCSQKIK--------------CRGGKDN-- 55
            |.|.....:|:..||::||.|  |.:.:.|.:....|..:.:              |...::|
Mouse     9 KSFQHYCAEFIRHSQQIGDGW--EWRTAKECSDGYMCKTQFRIKNETLTPHASVLTCLPTEENLE 71

  Fly    56 -------------SAELVSVEYHVVFSVSYQVPMLFFQAHRSDGSLLDVEATWRMFMPESKASDL 107
                         .||::..||||::|.|||||:|:|:|...||..|.:|..|         ..:
Mouse    72 LPMDDSEVTRPAAVAEVIKHEYHVLYSCSYQVPVLYFRASFLDGRPLALEDIW---------EGV 127

  Fly   108 HQ------------ILTQMDHPVLFRPFMALHPCRTAE----VLKQFGK--PSCNQVLTFISLYG 154
            |:            .:||.:||:|.:||..||||:|.|    |||...|  .:.|.:.:::||.|
Mouse   128 HECYKPRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTAVLKNSQKINRNVNYITSWLSLVG 192

  Fly   155 PHVQLHLQNAY 165
            |.|.|:|..:|
Mouse   193 PVVGLNLPLSY 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg10	NP_001097215.1	Autophagy_act_C	66..130	CDD:281917	26/75 (35%)
Atg10	NP_080046.3	Autophagy_act_C	95..162	CDD:367758	25/84 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I11256
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I5204
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005851
OrthoInspector	1	1.000	-	-		oto93602
orthoMCL	1	0.900	-	-		OOG6_104820
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3745
SonicParanoid	1	1.000	-	-		X6351
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.890