Protein Alignment CG14767 and LAPTM4A

DIOPT Version :10

• Sequence 1: NP_724705.1
• Gene: CG14767 / 50250
• FlyBaseID: FBgn0040777
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_055528.1
• Gene: LAPTM4A / 9741
• HGNCID: 6924
• Length: 233
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 77/272 - (28%)
• Similarity: 115/272 - (42%)
• Gaps: 53/272 - (19%)

  Fly    26 SSSSTGNRHLKEFT--CCFGLHVHTATLMIGLWHLFLNILALSVLAVIWRNPEMMDELEGGTHDY 88
            |.|...||..:.::  ||...||.|.|:::|.|::.:|:|...:|.|...:|..|
Human     3 SMSFKRNRSDRFYSTRCCGCCHVRTGTIILGTWYMVVNLLMAILLTVEVTHPNSM---------- 57

  Fly    89 TVDLSAPALPTPLSKVEPPYAYRDHSLNYRKRYQNFDMGGLVC------TCMIAITLMMIYGTIK 147
                  ||:......:.          ||   |.:..|....|      ..|..|:.|::||.|.
Human    58 ------PAVNIQYEVIG----------NY---YSSERMADNACVLFAVSVLMFIISSMLVYGAIS 103

  Fly   148 GKPSHLLPFFCLQLFDFAITTLTAAGYLCYLQAIHSIIAESHRLPWREKLLELPPEELVVVVLVV 212
            .:...|:||||.:||||.::.|.|...|.||..|...:.:....|:::.||.|....|:.:|||.
Human   104 YQVGWLIPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQLPDFPYKDDLLALDSSCLLFIVLVF 168

  Fly   213 FICIVFLKAYCIGIVWRCYKYLTLRQQHVRTLFPFLEPPTGVHSVGGTFGAEERSYSTLLPNYDE 277
            |...:..|||.|..||.||||:..|......::|..|.|.                ..:||.|:.
Human   169 FALFIIFKAYLINCVWNCYKYINNRNVPEIAVYPAFEAPP----------------QYVLPTYEM 217

  Fly   278 AIAQYLKQAPPP 289
            |:....|:.|||
Human   218 AVKMPEKEPPPP 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14767	NP_724705.1	Mtp	128..291	CDD:470991	53/168 (32%)
LAPTM4A	NP_055528.1	mtp	10..221	CDD:273274	70/255 (27%)