Protein Alignment CG14767 and LAPTM4B

DIOPT Version :10

• Sequence 1: NP_724705.1
• Gene: CG14767 / 50250
• FlyBaseID: FBgn0040777
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_060877.4
• Gene: LAPTM4B / 55353
• HGNCID: 13646
• Length: 226
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 68/258 - (26%)
• Similarity: 108/258 - (41%)
• Gaps: 53/258 - (20%)

  Fly    39 TCCFGLHVHTATLMIGLWHLFLNILALSVLAVIWRNPEMMD----ELEGGTHDYTVDLSAPALPT 99
            :||...||.|.|:::|:|:|.:|.:.|.:|.....:|:..:    || ||..::..|
Human    14 SCCLCCHVRTGTILLGVWYLIINAVVLLILLSALADPDQYNFSSSEL-GGDFEFMDD-------- 69

  Fly   100 PLSKVEPPYAYRDHSLNYRKRYQNFDMGGLVCTCMIAITLMMIYGTIKGKPSHLLPFFCLQLFDF 164
                                  .|..:...:...||.|..|..||..|.:.:.::||||.|:|||
Human    70 ----------------------ANMCIAIAISLLMILICAMATYGAYKQRAAWIIPFFCYQIFDF 112

  Fly   165 AITTLTAAGYLCYLQAIHSIIAE-SHRLPWREKLLELPPEELVVVVLVVFICIVFLKAYCIGIVW 228
            |:..|.|...|.|..:|...|.: ....|:|:.::.:.|..||:::|:....|:..|.|.|..||
Human   113 ALNMLVAITVLIYPNSIQEYIRQLPPNFPYRDDVMSVNPTCLVLIILLFISIILTFKGYLISCVW 177

  Fly   229 RCYKYLTLRQQHVRTLFPFLEPPTGVHSVGGTFGAEERSYSTLLPNYDEAIAQYLKQAPPPSY 291
            .||:|:                 .|.:|............:.|||.||:|......:.|||.|
Human   178 NCYRYI-----------------NGRNSSDVLVYVTSNDTTVLLPPYDDATVNGAAKEPPPPY 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14767	NP_724705.1	Mtp	128..291	CDD:470991	48/163 (29%)
LAPTM4B	NP_060877.4	Mtp	9..226	CDD:470991	68/258 (26%)