DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prosap and SLC9A3R1

DIOPT Version :9

Sequence 1:NP_610925.3 Gene:Prosap / 50225 FlyBaseID:FBgn0040752 Length:1871 Species:Drosophila melanogaster
Sequence 2:NP_004243.1 Gene:SLC9A3R1 / 9368 HGNCID:11075 Length:358 Species:Homo sapiens


Alignment Length:387 Identity:93/387 - (24%)
Similarity:138/387 - (35%) Gaps:109/387 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   691 SSATAPRIKKSAYNAPRSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVA 755
            ::|.||        .||...|.:...|:||.|.|.|....             ||:..|:||..|
Human     5 AAAGAP--------LPRLCCLEKGPNGYGFHLHGEKGKLG-------------QYIRLVEPGSPA 48

  Fly   756 DMAGLRPGDFLLTINGEDVTSASHEQVVEMIRSAGALVNLTVVSPQFPHQMQ----------ASA 810
            :.|||..||.|:.:|||:|...:|:|||..||:|...|.|.||.|:...|:|          ..|
Human    49 EKAGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRA 113

  Fly   811 QYLPSGAR-------AGSHHLNSGPSTPQSSHRQCATLPRKMT---GPGGSG-----PGSSSGGS 860
            |..|..|.       .|:.:.|......:|...|....||..|   ||.|.|     ..|..|..
Human   114 QEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQF 178

  Fly   861 VRMAPMPPRRDPKTTLSVGRARAK-----------------SMVAGLENGG--------EKEDDL 900
            :|..      ||.:.......||:                 .:|:.:..||        ::|.|.
Human   179 IRSV------DPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETDE 237

  Fly   901 PHTKSN---SVESIATPTPTGIQTGPGTPVQLRTASIKARPTSSRITAAELEELFQRQQGEGSAA 962
            ...|..   |.|.:..|.|.....|            :.:..:||...||            :|.
Human   238 FFKKCRVIPSQEHLNGPLPVPFTNG------------EIQKENSREALAE------------AAL 278

  Fly   963 NASRYATMMTSSRFQSGTDSGAATPPASN----GSPMRSGPLVYGSVA-EMKRKTARSKHGS 1019
            .:.|.|.:.::|...|...:...:||..:    .|...|.|::..::: .|.::.|..|..|
Human   279 ESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISLAMAKERAHQKRSS 340

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ProsapNP_610925.3 FERM_f0 20..103 CDD:293120
Ank_2 128..222 CDD:289560
ANK 131..233 CDD:238125
ANK repeat 157..189 CDD:293786
ANK 186..312 CDD:238125
ANK repeat 191..222 CDD:293786
Ank_2 196..322 CDD:289560
ANK repeat 224..289 CDD:293786
ANK repeat 291..322 CDD:293786
ANK repeat 324..353 CDD:293786
SH3 532..586 CDD:302595
PDZ_signaling 706..798 CDD:238492 34/91 (37%)
SLC9A3R1NP_004243.1 PDZ_signaling 12..91 CDD:238492 34/91 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 114..192 19/83 (23%)
PDZ_signaling 152..231 CDD:238492 17/84 (20%)
EBP50_C 235..358 CDD:312529 25/130 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 277..358 14/64 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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