DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosap and si:dkey-276j7.2

DIOPT Version :9

Sequence 1:	NP_610925.3	Gene:	Prosap / 50225	FlyBaseID:	FBgn0040752	Length:	1871	Species:	Drosophila melanogaster
Sequence 2:	XP_017212076.1	Gene:	si:dkey-276j7.2 / 792667	ZFINID:	ZDB-GENE-131127-420	Length:	250	Species:	Danio rerio

Alignment Length:	187	Identity:	42/187 - (22%)
Similarity:	72/187 - (38%)	Gaps:	42/187 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   623 AASYQGSPQLSLGGHSGSSSTLLQQPHQSPSLSVASNGSCQQPLESNEGGASGNGINNRNNNHSV 687
            :||.|...:| ||..|.:::.||...|:..    .....|:  ...|:.|        :.....|
Zfish    10 SASVQYIRKL-LGKSSCATNNLLNTGHKIQ----RKTSDCK--TTKNKDG--------KTLTRKV 59

  Fly   688 GQYSSATAPR-IKKSAYNAPRSVVLHRAK-RGFGFILRGAKASSQLMQLRPSERFPALQYLDDVD 750
            .|....||.: |:|       ||:|.|.: ..|||         ::..|.|...|        |.
Zfish    60 VQTQDKTAEQCIRK-------SVILRRTENETFGF---------EIQDLVPCVCF--------VK 100

  Fly   751 PGGVADMAGLRPGDFLLTINGEDVTSASHEQVVEMIRSAGALVNLTVVSPQFPHQMQ 807
            ...:|:.:||...|.::.:|...:...:.:|:.::.:.|..|: |.:|......|.|
Zfish   101 EDSLAESSGLMTDDVIIAVNSVSIAEFTQQQLKDLFQKASILM-LEIVRSSTEKQRQ 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosap	NP_610925.3	FERM_f0	20..103	CDD:293120
		Ank_2	128..222	CDD:289560
		ANK	131..233	CDD:238125
		ANK repeat	157..189	CDD:293786
		ANK	186..312	CDD:238125
		ANK repeat	191..222	CDD:293786
		Ank_2	196..322	CDD:289560
		ANK repeat	224..289	CDD:293786
		ANK repeat	291..322	CDD:293786
		ANK repeat	324..353	CDD:293786
		SH3	532..586	CDD:302595
		PDZ_signaling	706..798	CDD:238492	20/92 (22%)
si:dkey-276j7.2	XP_017212076.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910