| Sequence 1: | NP_610925.3 | Gene: | Prosap / 50225 | FlyBaseID: | FBgn0040752 | Length: | 1871 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_021327106.1 | Gene: | shank1 / 568908 | ZFINID: | ZDB-GENE-130530-691 | Length: | 2469 | Species: | Danio rerio |
| Alignment Length: | 2165 | Identity: | 530/2165 - (24%) |
|---|---|---|---|
| Similarity: | 779/2165 - (35%) | Gaps: | 682/2165 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 12 PPEPRDGWLLVRIHVPELNVYKCLQFPSERLVWDVKQQVLASLPKELKESFNYGLFAPPANGKAG 76
Fly 77 KFLDEERRLGDYP--FNGPVGYLELKYKRRVYKMLTLDERQLKALHTRANLRRFLECINGGHVEK 139
Fly 140 IAKMCAKGLDPNFHCSESGDTPLTVATGAKK-PNKLLIALVNGGALLDYRTKDGSTALHRAVEHD 203
Fly 204 SLEAVSTLLELGASPNYRDGRGITPLYISITRKCEAKITESLLHDHATLGIQDSQGWNEVHQACR 268
Fly 269 HGLVQHLEHLLFYGADMDGRNASGNSPLHVCAVNNQEACARMLLFRGAQRGAQNFANQTPYQVAV 333
Fly 334 IAGNLELAEIIENYKSEDIVPFRGPPRYNPKRRSG---IG--------------------WLSAN 375
Fly 376 GAAGAALLAAAGGGFGGAMVGSN---GAANGNNGAGGVGLMLSHQNHQQHHAGHHQQQHMHHQHH 437
Fly 438 QNHHQQLQQQQLPHLHTLQLHGPPSPCPSEHMLGAYSSASSSLSEG-SSGHRSHEDDISIVTDKS 501
Fly 502 LGDTSDIISDSSG---VGTNSDSAACSIGHPSTTVVCMEPYAGNTVGHIRLQPGDVIEVVGSTDC 563
Fly 564 GLLEGYVRGTNQSGFFPADCVQEVSLRQKHITNVMTASTGMAPQQQQQQHLQQAPAGSSAASYQG 628
Fly 629 SPQLSLGGHSGSSSTLLQQPHQSPSLSVASNGSCQQPLESNEGGASGNGINNRNNNHSVGQYSSA 693
Fly 694 TAPRIKKSAYNAPRSVVLHRAK--RGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVAD 756
Fly 757 MAGLRPGDFLLTINGEDVTSASHEQVVEMIRSAGALVNLTVVSPQFPHQMQASAQYLPSGARAGS 821
Fly 822 HHLNSGPSTPQSSHRQCATLPRKMTGPGGSGPGSSSGGSVRMAPMPPRRDPKTTLSVGRARAKSM 886
Fly 887 VAGLE-------------------NGGEKEDDLPHTKSNSVESIATPTPTGIQT--GPGTPVQLR 930
Fly 931 TASIKARPTSSRITAAELEELFQRQQGEG--SAANASRYATMMTSSRFQSGTDSGAAT----PP- 988
Fly 989 -----ASNGSPMRSGPLVYGSVAEMKRKTARSKHGSGTLRGKPVATPTVGPGGAGGGRDLKRFHS 1048
Fly 1049 TPDL--HGPQLHGSASSIWQASGKGHHSQ-------------------------DDVATLHASLQ 1086
Fly 1087 -RLNSNQGELKLGG-----LGAGSATGAGGAVLPPP-NHPPPPPPVGQVVKVETRSSVSEYESTI 1144
Fly 1145 SLQQKLKKRTENDAVTSAAIDGVQSSFNPSANAKIYASPQELRNVMAWKLRQAQEKPSQETSAGS 1209
Fly 1210 QQ---PVSQYAAPTQMRPAQQQQ----QAQQPPTALASHYAAPQVQVQQVQQVQQSPQQSAPQSP 1267
Fly 1268 PAPPLPQAAP--VPAQNGNGNGSTSGAGSAPPIPE-PDYSCSES-DGEDENSILVA--------R 1320
Fly 1321 NTKLNEKIALFDVPETSGNSQASGSSSNSGSASIS-HSLSVEEIQRIRSN-------------LK 1371
Fly 1372 TSKSSPNGFAKKPEEEKPQQEQQQSHQQPQQLLQPGEDECDNSSSGVSSEQEQLALAAGVTL--- 1433
Fly 1434 PGGGKPTDTIKKKPS----VTIVEEPKTIPD--------------------------QPSSNTSH 1468
Fly 1469 TTKPMAKTTISIGGGGSA-------VPTATLTVKQLVQQQHAPVIQQ-------QQQQLGSKQPV 1519
Fly 1520 TAASTN--------KFTQQSNINSNVMSPQVLGRIPSHHHQQQSSNP------------------ 1558
Fly 1559 -----NQKLIATQQQILQQQQQQLAHQQHLQQILKAKAAA----------------------AGG 1596
Fly 1597 ASNTAVLVAKHQQKLHKGTSSGHESEMETRSDLEDDDGDLSPSPP----AKAFQR---------H 1648
Fly 1649 NSLTRKQ-------------AAAIAMQRGATRTTAVSLMQLPPPLEADS--------DGEPSQLT 1692
Fly 1693 LQRQQSHHPSQTHPHPHQLQQQLQLQQQQQQ------------------QQQQQQPMAAHIVG-- 1737
Fly 1738 MLPSGQLVAVASGAVAGVP---GVGATAVQ-QGNNNLQQLC--TDNLVLAPPPQFCDCNDAKHAP 1796
Fly 1797 QPHL---------------PTSQYHPQQQQQQQHQQQQ----QQQQQLQQQLQQQQMLQMHQRLS 1842
Fly 1843 GG--------AGAGAVGTLG 1854 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Prosap | NP_610925.3 | FERM_f0 | 20..103 | CDD:293120 | 38/84 (45%) |
| Ank_2 | 128..222 | CDD:289560 | 43/94 (46%) | ||
| ANK | 131..233 | CDD:238125 | 49/102 (48%) | ||
| ANK repeat | 157..189 | CDD:293786 | 12/32 (38%) | ||
| ANK | 186..312 | CDD:238125 | 66/125 (53%) | ||
| ANK repeat | 191..222 | CDD:293786 | 16/30 (53%) | ||
| Ank_2 | 196..322 | CDD:289560 | 66/125 (53%) | ||
| ANK repeat | 224..289 | CDD:293786 | 33/64 (52%) | ||
| ANK repeat | 291..322 | CDD:293786 | 17/30 (57%) | ||
| ANK repeat | 324..353 | CDD:293786 | 13/28 (46%) | ||
| SH3 | 532..586 | CDD:302595 | 17/53 (32%) | ||
| PDZ_signaling | 706..798 | CDD:238492 | 46/93 (49%) | ||
| shank1 | XP_021327106.1 | FERM_f0 | 151..234 | CDD:318667 | 37/82 (45%) |
| Ank_2 | <258..>363 | CDD:330894 | 48/104 (46%) | ||
| ANK repeat | 291..323 | CDD:293786 | 12/31 (39%) | ||
| ANK | 320..446 | CDD:238125 | 66/125 (53%) | ||
| ANK repeat | 325..356 | CDD:293786 | 16/30 (53%) | ||
| ANK repeat | 358..423 | CDD:293786 | 33/64 (52%) | ||
| ANK | 421..>481 | CDD:238125 | 31/59 (53%) | ||
| ANK repeat | 425..456 | CDD:293786 | 17/30 (57%) | ||
| SH3_Shank | 610..659 | CDD:212766 | 19/69 (28%) | ||
| PDZ_signaling | 704..797 | CDD:238492 | 46/92 (50%) | ||
| Atrophin-1 | <2236..2376 | CDD:331285 | |||
| SAM_Shank1,2,3 | 2374..2439 | CDD:188905 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C170582294 | |
| Domainoid | 1 | 1.000 | 72 | 1.000 | Domainoid score | I9300 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D133974at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 1 | 1.000 | - | - | otm25540 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_103134 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X750 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| ZFIN | 0 | 0.000 | Not matched by this tool. | |||
| 7 | 6.750 | |||||