Protein Alignment OXCT1 and SCOT

DIOPT Version :9

• Sequence 1: NP_001351228.1
• Gene: OXCT1 / 5019
• HGNCID: 8527
• Length: 527
• Species: Homo sapiens
• Sequence 2: NP_647683.1
• Gene: SCOT / 38261
• FlyBaseID: FBgn0035298
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 310/520 - (59%)
• Similarity: 393/520 - (75%)
• Gaps: 17/520 - (3%)

Human     8 SSGLRLCASARGSGATWYKGCVCSFSTSAHRHTKFYTDPVEAVKDIPDGATVLVGGFGLCGIPEN 72
            |.|.|..||        .|...|..::...|:.|.|...::||.|:.|||.:|.||||:|||||.
  Fly    10 SLGARYTAS--------IKAIACYSTSGKQRNGKIYESAIDAVADVQDGAQILFGGFGICGIPEK 66

Human    73 LIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTP 137
            :|:||.:.|||.:|.||||.|||:.|||:|::.||:.:::.||||||.|..||||.|||.|||||
  Fly    67 MINALKQKGVKNITGVSNNGGVDDTGLGVLIKQKQVSKVIGSYVGENTELVRQYLEGELAVELTP 131

Human   138 QFFLRLREGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQ 202
            |       |||||:|||||||:|||||||||.|||||||:||||:|||.|.|:|:.:.|:||||:
  Fly   132 Q-------GTLAEKIRAGGAGIPAFYTPTGYATLVQEGGAPIKYSKDGKVEISSEKKPVKEFNGK 189

Human   203 HFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIH 267
            ::::||:|..|||.|||.|||..||::|.|:|||||.|||:||:.||.||||||.|||.:|::||
  Fly   190 NYVMEESIFADFAFVKAQKADPLGNLVFNKAARNFNAPMCRAAKITVAEVEEIVPIGALSPDEIH 254

Human   268 IPQIYVHRLIKGEKYEKRIERLSIR--KEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGI 330
            :|.||::|:.||..|.||:|||.|.  |:....|....|...:||||.:|.||||.|||||||||
  Fly   255 VPGIYINRIFKGTNYNKRVERLRITEPKDPSKPAPPPNPAQVLRERIARRVALEFHDGMYANLGI 319

Human   331 GIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAM 395
            |||:|:||:|...:.|.||||||:|||||:|.:.:.|.||||||||:||::||||:|.||:||||
  Fly   320 GIPVLSSNYIPKGMNVMLQSENGILGLGPFPTKDKVDPDLINAGKESVTVVPGASYFGSDDSFAM 384

Human   396 IRGGHVDLTMLGAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIM 460
            |||||||:|:||||:||..|||||||||||:|||||||||||::..|||::||||:|:..:.||:
  Fly   385 IRGGHVDITILGAMEVSATGDLANWMIPGKLVKGMGGAMDLVAAPGTKVIITMEHNARDGSPKIL 449

Human   461 EKCTLPLTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQI 525
            :.|:||||||..::.||:|||||.|:|..||||||:.||.||||:..|||..|.|||.|..|.||
  Fly   450 DTCSLPLTGKGVIDMIISEKAVFTVEKGVGLTLIEVAEGYTVDDIIASTGAKFTVSPNLKKMGQI 514

Human   526  525
              Fly   515  514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OXCT1	NP_001351228.1	AtoD	41..281	CDD:224702	147/239 (62%)
		SugarP_isomerase	307..515	CDD:320918	138/207 (67%)
SCOT	NP_647683.1	AtoD	35..268	CDD:224702	147/239 (62%)
		pcaJ_scoB_fam	298..504	CDD:188219	138/205 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159880
Domainoid	1	1.000	314	1.000	Domainoid score	I1287
eggNOG	1	0.900	-	-		E1_COG2057
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H377
Inparanoid	1	1.050	631	1.000	Inparanoid score	I846
Isobase	1	0.950	-	0	Normalized mean entropy	S2149
OMA	1	1.010	-	-		QHG60825
OrthoDB	1	1.010	-	-		D332119at33208
OrthoFinder	1	1.000	-	-		FOG0002929
OrthoInspector	1	1.000	-	-		otm40593
orthoMCL	1	0.900	-	-		OOG6_100924
Panther	1	1.100	-	-	LDO	PTHR13707
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2787
SonicParanoid	1	1.000	-	-		X1930
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750