DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18675 and Cfap298

DIOPT Version :9

Sequence 1:	NP_652334.2	Gene:	CG18675 / 50169	FlyBaseID:	FBgn0040696	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	NP_080778.2	Gene:	Cfap298 / 68001	MGIID:	1915251	Length:	290	Species:	Mus musculus

Alignment Length:	290	Identity:	148/290 - (51%)
Similarity:	209/290 - (72%)	Gaps:	0/290 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVLLQVKRGDELIFLYETSVKEKTDTVLRELVALHNGQLKIQRVCMEIEELAEHGTMVPPEMIGL 65
            ||:|.||||||..||.:.....:.:.:..::..::||:||:.|:|.|:|||||||..:||.|.||
Mouse     1 MVVLHVKRGDESQFLLQAPGSTELEELTAQVARVYNGRLKVHRLCSEMEELAEHGVFLPPNMQGL 65

  Fly    66 NEEQREELKLKDVWADKCIPSGGFTINKDPLLRRNGQQPTEAMQKVLAGAMNDAKAMVDRRLAKS 130
            .:||.|||||||.|.:||:||||....||.:.|||||.|.|.|::||...:.:|||:|.::..::
Mouse    66 TDEQIEELKLKDEWGEKCVPSGGSVFTKDEIGRRNGQAPNEKMKQVLKKTVEEAKAIVSKKQVEA 130

  Fly   131 SKTLTPKIVEEALNLLRGGVTIVYPMQLPPHDSIRMEFTNTEDLTGTQASKEVIEPSKAQFWFAG 195
            ...:|.::|::||:.|||.|.|||||.|||:|.|||||.|.|||:||||:.|||:.|:||.|:|.
Mouse   131 GVFVTMEMVKDALDQLRGAVMIVYPMGLPPYDPIRMEFENKEDLSGTQAALEVIQESEAQLWWAA 195

  Fly   196 HQMLMGKLMSDYLGHNDKTKVVVKLNQIGEGPPGREAVISDPLRRQMMAEAYRRQEELKKLEQDD 260
            .::...|.:|||:|.|:|||::||:.|.|:|.|.||.|||....:|:|...:||||||||||::|
Mouse   196 KELRRTKKLSDYVGKNEKTKIIVKIQQRGQGAPAREPVISSEEHKQLMLFYHRRQEELKKLEEND 260

  Fly   261 DDEYLNSSWADSGSLKRQAHGLENVRFRFR 290
            ||..|||.|||:.:|||..||::::::|.|
Mouse   261 DDSCLNSPWADNTALKRHFHGVKDIKWRPR 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18675	NP_652334.2	DUF2870	189..285	CDD:287980	50/95 (53%)
Cfap298	NP_080778.2	DUF2870	189..285	CDD:287980	50/95 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848913
Domainoid	1	1.000	198	1.000	Domainoid score	I3096
eggNOG	1	0.900	-	-		E1_2CME9
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10941
Inparanoid	1	1.050	305	1.000	Inparanoid score	I2611
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56791
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008355
OrthoInspector	1	1.000	-	-		oto94970
orthoMCL	1	0.900	-	-		OOG6_104560
Panther	1	1.100	-	-	LDO	PTHR13238
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4526
SonicParanoid	1	1.000	-	-		X6334
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790