DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18675 and Cfap298

DIOPT Version :9

Sequence 1:	NP_652334.2	Gene:	CG18675 / 50169	FlyBaseID:	FBgn0040696	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	NP_001008289.1	Gene:	Cfap298 / 288269	RGDID:	1306954	Length:	290	Species:	Rattus norvegicus

Alignment Length:	290	Identity:	148/290 - (51%)
Similarity:	208/290 - (71%)	Gaps:	0/290 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVLLQVKRGDELIFLYETSVKEKTDTVLRELVALHNGQLKIQRVCMEIEELAEHGTMVPPEMIGL 65
            ||:|.||||||..||.:.....:.:.:..::..::||:||:.|:|.|||||||||..:||.|.||
  Rat     1 MVVLHVKRGDESQFLLQAPGSTELEELTAQVTRVYNGRLKVHRLCTEIEELAEHGVFLPPNMQGL 65

  Fly    66 NEEQREELKLKDVWADKCIPSGGFTINKDPLLRRNGQQPTEAMQKVLAGAMNDAKAMVDRRLAKS 130
            .:||.|||||||.|.:||:||||....||.:.||||..|.|.|::||...:.:|||||.::..::
  Rat    66 TDEQIEELKLKDEWGEKCVPSGGSVFTKDDIGRRNGHAPNEKMKQVLKKTVEEAKAMVSKKQVEA 130

  Fly   131 SKTLTPKIVEEALNLLRGGVTIVYPMQLPPHDSIRMEFTNTEDLTGTQASKEVIEPSKAQFWFAG 195
            ...:|.::|::||:.|||.|.|||||.|||:|.|||||.|.|||:||||:.|||:.|:||.|:|.
  Rat   131 GVFVTMEMVKDALDQLRGAVMIVYPMGLPPYDPIRMEFENKEDLSGTQAALEVIQESEAQLWWAA 195

  Fly   196 HQMLMGKLMSDYLGHNDKTKVVVKLNQIGEGPPGREAVISDPLRRQMMAEAYRRQEELKKLEQDD 260
            .::...|.:|||:|.|:|||::||:.|.|:|.|.||.:||....:|:|...:||||||||||::|
  Rat   196 KELRRTKKLSDYVGKNEKTKIIVKIQQRGQGAPAREPLISSEEHKQLMLFYHRRQEELKKLEEND 260

  Fly   261 DDEYLNSSWADSGSLKRQAHGLENVRFRFR 290
            ||..|||.|||:.:|||..||::::::|.|
  Rat   261 DDSCLNSPWADNTALKRHFHGVKDIKWRPR 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18675	NP_652334.2	DUF2870	189..285	CDD:287980	49/95 (52%)
Cfap298	NP_001008289.1	DUF2870	189..285	CDD:287980	49/95 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352521
Domainoid	1	1.000	198	1.000	Domainoid score	I2997
eggNOG	1	0.900	-	-		E1_2CME9
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10941
Inparanoid	1	1.050	306	1.000	Inparanoid score	I2554
OMA	1	1.010	-	-		QHG56791
OrthoDB	1	1.010	-	-		D1079968at2759
OrthoFinder	1	1.000	-	-		FOG0008355
OrthoInspector	1	1.000	-	-		oto98467
orthoMCL	1	0.900	-	-		OOG6_104560
Panther	1	1.100	-	-	LDO	PTHR13238
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6334
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770