DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18675 and cfap298

DIOPT Version :9

Sequence 1:	NP_652334.2	Gene:	CG18675 / 50169	FlyBaseID:	FBgn0040696	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	XP_004912205.1	Gene:	cfap298 / 100380199	XenbaseID:	XB-GENE-5910469	Length:	290	Species:	Xenopus tropicalis

Alignment Length:	290	Identity:	144/290 - (49%)
Similarity:	216/290 - (74%)	Gaps:	0/290 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVLLQVKRGDELIFLYETSVKEKTDTVLRELVALHNGQLKIQRVCMEIEELAEHGTMVPPEMIGL 65
            ||.|.||:|||..||::|||....:.:::::.|::||:||::|:|.|:.||||||..:||.|.||
Frog     1 MVRLHVKKGDESQFLFDTSVTVSVEELVKQITAIYNGRLKVERICSEMAELAEHGITMPPNMQGL 65

  Fly    66 NEEQREELKLKDVWADKCIPSGGFTINKDPLLRRNGQQPTEAMQKVLAGAMNDAKAMVDRRLAKS 130
            .:||.|:|||||.||::|:||||....||.:.||||..|.::|:|||...|.:|||::.::.|::
Frog    66 ADEQIEDLKLKDEWAERCVPSGGSVFKKDEIGRRNGHAPNDSMKKVLQKTMEEAKALISKKQAEA 130

  Fly   131 SKTLTPKIVEEALNLLRGGVTIVYPMQLPPHDSIRMEFTNTEDLTGTQASKEVIEPSKAQFWFAG 195
            :..:|.::|:||.:.|||...|||||.|||||.|||||.|.|||:||.|.:.|||..::|.|:||
Frog   131 NVCVTLEMVKEATDQLRGAAMIVYPMGLPPHDPIRMEFENNEDLSGTHAGQLVIEEPESQLWWAG 195

  Fly   196 HQMLMGKLMSDYLGHNDKTKVVVKLNQIGEGPPGREAVISDPLRRQMMAEAYRRQEELKKLEQDD 260
            .::...:.:|||:|.|:|||::||:.:.|:|.||||.|:|:..::::|...|||||||||||:|:
Frog   196 KELQRKQKLSDYVGKNEKTKIIVKIQKRGQGAPGREPVVSEEEQKKLMMHYYRRQEELKKLEEDE 260

  Fly   261 DDEYLNSSWADSGSLKRQAHGLENVRFRFR 290
            |..|:|:.||||.|||||..|:::::::.|
Frog   261 DISYMNAEWADSNSLKRQFQGVKDIKWKPR 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18675	NP_652334.2	DUF2870	189..285	CDD:287980	48/95 (51%)
cfap298	XP_004912205.1	DUF2870	190..285	CDD:371364	48/94 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	203	1.000	Domainoid score	I2924
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10941
Inparanoid	1	1.050	312	1.000	Inparanoid score	I2538
OMA	1	1.010	-	-		QHG56791
OrthoDB	1	1.010	-	-		D1079968at2759
OrthoFinder	1	1.000	-	-		FOG0008355
OrthoInspector	1	1.000	-	-		oto105159
Panther	1	1.100	-	-	LDO	PTHR13238
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4526
SonicParanoid	1	1.000	-	-		X6334
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110