DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30158 and DIRAS3

DIOPT Version :9

Sequence 1:	NP_652315.2	Gene:	CG30158 / 50149	FlyBaseID:	FBgn0050158	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_004666.1	Gene:	DIRAS3 / 9077	HGNCID:	687	Length:	229	Species:	Homo sapiens

Alignment Length:	169	Identity:	60/169 - (35%)
Similarity:	93/169 - (55%)	Gaps:	9/169 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RLVLLGGAGVGKSSIVKRFLFKTYTDKYRATVEDLYNREYDLGGVTLKVDILDT-SGDMQFPAMR 71
            |:|::|.||||||:::.::....:..:|..|:|:.|.:........|.:.|.|: |||.. .|::
Human    39 RVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKSGDGN-RALQ 102

  Fly    72 RLSIATAHAFMLVYAATSAPSFQCVKQCFEEIREQRG-DFQDIPIVIAGNKADLATTHREVKLEE 135
            |..||..|||:|||:.|...:.:.:|..:|.|.:.:| :....|||:.|||:|  .|||||.|
Human   103 RHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIVLVGNKSD--DTHREVAL-- 163

  Fly   136 VTDWVFCELPRLRAKVLECSAKEDSNVTDLFKSLLSLSR 174
             .|...|.: ......:|.|||.|.||.:||..||:..:
Human   164 -NDGATCAM-EWNCAFMEISAKTDVNVQELFHMLLNYKK 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30158	NP_652315.2	Ras	8..172	CDD:206642	60/165 (36%)
CG30158	NP_652315.2	Ras	8..170	CDD:278499	58/163 (36%)
DIRAS3	NP_004666.1	P-loop_NTPase	37..200	CDD:328724	60/167 (36%)
DIRAS3	NP_004666.1	Effector region. /evidence=ECO:0000255	66..74		3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910