Protein Alignment CG30158 and NKIRAS2

DIOPT Version :10

• Sequence 1: NP_652315.2
• Gene: CG30158 / 50149
• FlyBaseID: FBgn0050158
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_060065.2
• Gene: NKIRAS2 / 28511
• HGNCID: 17898
• Length: 191
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 57/197 - (28%)
• Similarity: 91/197 - (46%)
• Gaps: 27/197 - (13%)

  Fly     8 RLVLLGGAGVGKSSIVKRFLFKTYT--DKYRATVEDLY--NREYDLGGVTLKVDILDTSGDMQFP 68
            ::|:.|.|.|||:||:::.|:..:.  .:...|.||:|  :.|.| .||..:|...||.|.....
Human     6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETD-RGVREQVRFYDTRGLRDGA 69

  Fly    69 AMRRLSIATAHAFMLVYAATSAPSFQCVKQCFEEIREQRGDFQDIPIVIAGNKADLATTHREVKL 133
            .:.|...:....::|||:..|..|||.|:...:||.:.: |.:::.||:.|||.|| ...|.|..
Human    70 ELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSK-DKKEVTIVVLGNKCDL-QEQRRVDP 132

  Fly   134 EEVTDWVFCELPRLRAKVLECSAKEDSNVTDLF------------KSLLSLSRFLPASSSGSGGS 186
            :....|...|    :.|:.|.|..:..::.:.|            ||...|||    .:.|||..
Human   133 DVAQHWAKSE----KVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLSR----KNKGSGSL 189

  Fly   187 GG 188
            .|
Human   190 DG 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30158	NP_652315.2	Ras	8..172	CDD:206642	50/179 (28%)
NKIRAS2	NP_060065.2	Small GTPase-like	1..191		56/195 (29%)
		P-loop containing Nucleoside Triphosphate Hydrolases	6..168	CDD:476819	48/168 (29%)
		Effector region	35..43		3/7 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..191		8/25 (32%)