DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30158 and RHEBL1

DIOPT Version :9

Sequence 1:	NP_652315.2	Gene:	CG30158 / 50149	FlyBaseID:	FBgn0050158	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_653194.1	Gene:	RHEBL1 / 121268	HGNCID:	21166	Length:	183	Species:	Homo sapiens

Alignment Length:	167	Identity:	49/167 - (29%)
Similarity:	90/167 - (53%)	Gaps:	14/167 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RLVLLGGAGVGKSSIVKRFLFKTYTDKYRATVEDLYNREYDLGGVTLKVDILDTSGDMQFPAMRR 72
            ::|:||...|||:|:..:|:...:::.|..|||:.|::...||.....:.::||:|..::..:..
Human     8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEYSILPY 72

  Fly    73 LSIATAHAFMLVYAATSAPSFQCVKQCFEEIREQRGDFQDIPIVIAGNKADLATTHREVKLEE-- 135
            ..|...|.::|||:.||..|||.::..::::.|..|..: :|:|:.|||||| :..|||:..|
Human    73 SFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTR-VPVVLVGNKADL-SPEREVQAVEGK 135

  Fly   136 --VTDWVFCELPRLRAKVLECSAKEDSNVTDLFKSLL 170
              ...|        .|..:|.||:|:.....:|..::
Human   136 KLAESW--------GATFMESSARENQLTQGIFTKVI 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30158	NP_652315.2	Ras	8..172	CDD:206642	49/167 (29%)
CG30158	NP_652315.2	Ras	8..170	CDD:278499	49/165 (30%)
RHEBL1	NP_653194.1	small_GTPase	5..169	CDD:197466	49/167 (29%)
		RheB	6..183	CDD:206709	49/167 (29%)
		Effector region	35..43		4/7 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810