Protein Alignment OTX1 and CG11294

DIOPT Version :10

• Sequence 1: NP_055377.1
• Gene: OTX1 / 5013
• HGNCID: 8521
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_572500.1
• Gene: CG11294 / 31807
• FlyBaseID: FBgn0030058
• Length: 261
• Species: Drosophila melanogaster
• Alignment Length: 338
• Identity: 89/338 - (26%)
• Similarity: 129/338 - (38%)
• Gaps: 105/338 - (31%)

Human    17 LAGPAM-----DLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKIN 76
            :|||.:     |||   ..|....|:|||.|||||..||..|||||.||.|||:|:||||||:|:
  Fly     1 MAGPFISPLPGDLL---TEYMFGRRRQRRNRTTFTPQQLQELEALFQKTHYPDVFLREEVALRIS 62

Human    77 LPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSS 141
            |.|:||||||:|||||.|:|             .:...::::.........|||.:...|....|
  Fly    63 LSEARVQVWFQNRRAKWRKQ-------------ARLQLLQDAWRMRCLSLGTPPVMGGGAVQGGS 114

Human   142 ASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCM 206
            .:.::|.|           |.....:||:.:..|..:.....|.|...::..|          ..
  Fly   115 GNGATARP-----------PSQTPENLSSASKDSELAEVGNGPNSGSFTMMHP----------AF 158

Human   207 QRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSS 271
            |:           .:.....||..........|.:|   .:...|.||.|.    .:|..||  :
  Fly   159 QQ-----------QHQQQQHQGHQQATDQDKLSKTY---TELKLYKAPSHG----MELGGMA--A 203

Human   272 MAGHHHHHPHAHHPLSQSSGHHHHHHHHHHQGYGGSG---LAFNSADCLDYKE------------ 321
            ::|                        |..:|..||.   :...|..|:|:.:
  Fly   204 LSG------------------------HSDEGSDGSDSEEIDLTSGACIDFSQSSKLQQQQQQQQ 244

Human   322 ----PGAAAASSA 330
                .|||.::.|
  Fly   245 QQGTQGAAGSAEA 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OTX1	NP_055377.1	Homeodomain	39..95	CDD:459649	40/55 (73%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..146		9/54 (17%)
		TF_Otx	178..274	CDD:427350	15/95 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..305		6/47 (13%)
CG11294	NP_572500.1	Homeodomain	29..81	CDD:459649	37/51 (73%)