Protein Alignment CAH5 and CA7

DIOPT Version :10

• Sequence 1: NP_001097988.2
• Gene: CAH5 / 50102
• FlyBaseID: FBgn0040629
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_005173.1
• Gene: CA7 / 766
• HGNCID: 1381
• Length: 264
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 85/267 - (31%)
• Similarity: 125/267 - (46%)
• Gaps: 30/267 - (11%)

  Fly    43 YNYDEQGDDW--TGTCQSGENQSPIDLIFEDSKIVAIPRLRFNNYDQPLQ------TPLVITNNG 99
            |..|:....|  ......|:.||||::|  .|:.|..|.|      |||:      ..|.|||||
Human     9 YGQDDGPSHWHKLYPIAQGDRQSPINII--SSQAVYSPSL------QPLELSYEACMSLSITNNG 65

  Fly   100 HTANMVIPQTRGGQRPSINGSLLPGNFEAQSVHFHWGSREAKGSEHAINFQRYDVEMHIVHKNT- 163
            |:..  :.......|..:.|..|.|.:..:..|||||.:...||||.::.:.:..|:|:||.|.
Human    66 HSVQ--VDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAK 128

  Fly   164 IYETMGEATMHPDGLAVLGVMFRAVDRQTSQHYGLNKIFNQLPRIVQYNSNATITGRLTVGQLLG 228
            .|.|.|||...||||||:||.....|    :|..:|::.:.| .:|::..............||.
Human   129 KYSTFGEAASAPDGLAVVGVFLETGD----EHPSMNRLTDAL-YMVRFKGTKAQFSCFNPKCLLP 188

  Fly   229 NIVTGEFFTYNGSLTTPDCAEAVTWTVFPDVLDYPRRQITK----LWNLRDSRQRPLINNYRSIQ 289
              .:..::||.||||||..:|:|||.|..:.:....||:.|    |:...|..:..::||:|..|
Human   189 --ASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQ 251

  Fly   290 DTNSRDV 296
            ....|.|
Human   252 PLKGRVV 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH5	NP_001097988.2	Carb_anhydrase	50..299	CDD:459707	83/260 (32%)
CA7	NP_005173.1	alpha_CA_VII	27..262	CDD:239402	82/249 (33%)