Protein Alignment CAH5 and Car12

DIOPT Version :10

• Sequence 1: NP_001097988.2
• Gene: CAH5 / 50102
• FlyBaseID: FBgn0040629
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: XP_006511611.1
• Gene: Car12 / 76459
• MGIID: 1923709
• Length: 355
• Species: Mus musculus
• Alignment Length: 279
• Identity: 86/279 - (30%)
• Similarity: 135/279 - (48%)
• Gaps: 50/279 - (17%)

  Fly    49 GDDWTGTCQSGEN-------------QSPIDLIFEDSKIV----AIPRLRFNNYDQPLQTPLVIT 96
            |..||....:||.             ||||||   .|.|:    ::..|:|..|:..::..|.:|
Mouse    29 GSKWTYVGPAGEKNWSKKYPSCGGLLQSPIDL---HSDILQYDASLAPLQFQGYNVSVEKLLNLT 90

  Fly    97 NNGHTANMVIPQTRGGQRPSING-----SLLPGNFEAQSVHFHWGSR-EAKGSEHAINFQRYDVE 155
            |:||:.           |.::|.     .|.|.::.|:.:|.|||:| :..||||.::.:.:..|
Mouse    91 NDGHSV-----------RLNLNSDMYIQGLQPHHYRAEQLHLHWGNRNDPHGSEHTVSGKHFAAE 144

  Fly   156 MHIVHKNT-IYETMGEATMHPDGLAVLGVMFRAVDRQTSQHYGLNKIFNQLPRIVQYNSNATITG 219
            :||||.|: :|.....|:...:|||||.|:...    .|.:...:|||:.|.. |:|.....:..
Mouse   145 LHIVHYNSDLYPDFSTASDKSEGLAVLAVLIEI----GSANPSYDKIFSHLQH-VKYKGQQVLIP 204

  Fly   220 RLTVGQLLGNIVTGEFFTYNGSLTTPDCAEAVTWTVFPDVLDYPRRQI----TKLW--NLRDSRQ 278
            ...:.:||.. ..||::.|.||||||.|...|.||||.:.:...:.|:    |.|:  ::.|...
Mouse   205 GFNIEELLPE-SPGEYYRYEGSLTTPPCYPTVLWTVFRNPVQISQEQLLALETALYFTHMDDPTP 268

  Fly   279 RPLINNYRSIQDTNSRDVY 297
            |.:|||:|.:|..:.|.||
Mouse   269 REMINNFRQVQKFDERLVY 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH5	NP_001097988.2	Carb_anhydrase	50..299	CDD:459707	85/278 (31%)
Car12	XP_006511611.1	alpha_CA	39..290	CDD:469577	83/269 (31%)