Protein Alignment CAH5 and CA10

DIOPT Version :10

• Sequence 1: NP_001097988.2
• Gene: CAH5 / 50102
• FlyBaseID: FBgn0040629
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_064563.1
• Gene: CA10 / 56934
• HGNCID: 1369
• Length: 328
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 71/258 - (27%)
• Similarity: 124/258 - (48%)
• Gaps: 41/258 - (15%)

  Fly    56 CQSGENQSPIDLIFEDSKIVAIPRLRFNNYDQPLQTPLVITNNGHTANMVIPQTRGGQRPS---- 116
            |..|:.|||:::  |.|.::         :| |..|||.|...|...:..:..|  |:..|
Human    60 CSVGKRQSPVNI--ETSHMI---------FD-PFLTPLRINTGGRKVSGTMYNT--GRHVSLRLD 110

  Fly   117 ------INGSLLPGNFEAQSVHFHWGSREAKGSEHAINFQRYDVEMHIVHKN-TIYETMGEATMH 174
                  |:|..:..:...:.:..|:||.:::||||.:|.|.:..|:.::|.| .:|..:.||...
Human   111 KEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKS 175

  Fly   175 PDGLAVLGVMFRAVDRQTSQHYGLNKIFNQ--LPRIVQYNSNATITGRLTVGQLLGNIVTGEFFT 237
            |:||.|:.:..:..|   |.:..||::.|:  :.||. |.::|.:...|.:.:|...  |..|.|
Human   176 PNGLVVVSIFIKVSD---SSNPFLNRMLNRDTITRIT-YKNDAYLLQGLNIEELYPE--TSSFIT 234

  Fly   238 YNGSLTTPDCAEAVTWTVFPDVLDYPRRQITKLWNLRDSRQRP------LINNYRSIQDTNSR 294
            |:||:|.|.|.|..:|.:....:...|.|:..|..|  |:.:|      :.:|:|.:|..|:|
Human   235 YDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLL--SQNQPSQIFLSMSDNFRPVQPLNNR 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH5	NP_001097988.2	Carb_anhydrase	50..299	CDD:459707	71/258 (28%)
CA10	NP_064563.1	alpha_CARP_X_XI_like	46..302	CDD:239395	71/258 (28%)