Protein Alignment CAH5 and Ca5a

DIOPT Version :10

• Sequence 1: NP_001097988.2
• Gene: CAH5 / 50102
• FlyBaseID: FBgn0040629
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_062166.1
• Gene: Ca5a / 54233
• RGDID: 2243
• Length: 304
• Species: Rattus norvegicus
• Alignment Length: 278
• Identity: 80/278 - (28%)
• Similarity: 133/278 - (47%)
• Gaps: 44/278 - (15%)

  Fly    42 EYNYDEQGDD------WTGTCQS--GENQSPIDLIFEDSKIVAIPRLRFNNYDQPLQTPLVIT-- 96
            :::|.|:..:      |||...|  |..||||::.:.||.           || |...||.::
  Rat    35 QHSYAEKHSNCARHPLWTGPVSSPGGTQQSPINIQWTDSV-----------YD-PKLAPLRVSYD 87

  Fly    97 --------NNGHTANMVIPQTRGGQRPSINGSLLPGNFEAQSVHFHWGSREAKGSEHAINFQRYD 153
                    |.|:...:....:  .:...|:|..|..::..:..|||||:.:..||||.::...|.
  Rat    88 AASCRYLWNTGYFFQVEFDDS--CEESGISGGPLGNHYRLKQFHFHWGATDEWGSEHMVDGHAYP 150

  Fly   154 VEMHIVHKNTI-YETMGEATMHPDGLAVLGVMFRAVDRQTSQHYGLNKIFNQLPRIVQYNSNATI 217
            .|:|:||.|:: ||...:||...:||||:||..:.    .:.|..|.::.:.||.:...::..|:
  Rat   151 AELHLVHWNSMKYENYKKATTGENGLAVIGVFLKL----GAHHEALQRLVDILPEVRHKDTQVTM 211

  Fly   218 TGRLTVGQLLGNIVTGEFFTYNGSLTTPDCAEAVTWTVFPDVLDYPRRQI----TKLWNLRDSRQ 278
             |......||.  ...:::||.||||||..||:|||.|....::....|:    |.|::.|...:
  Rat   212 -GPFDPSCLLP--ACRDYWTYPGSLTTPPLAESVTWIVHKMPIEVSPSQLSTFRTLLFSGRGEDE 273

  Fly   279 RPLINNYRSIQDTNSRDV 296
            ..::||:|.:|....|:|
  Rat   274 EVMVNNFRPLQPLRGRNV 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH5	NP_001097988.2	Carb_anhydrase	50..299	CDD:459707	78/270 (29%)
Ca5a	NP_062166.1	alpha_CA	60..295	CDD:469577	74/253 (29%)