Protein Alignment CAH5 and Ca3

DIOPT Version :10

• Sequence 1: NP_001097988.2
• Gene: CAH5 / 50102
• FlyBaseID: FBgn0040629
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_062165.2
• Gene: Ca3 / 54232
• RGDID: 2241
• Length: 260
• Species: Rattus norvegicus
• Alignment Length: 263
• Identity: 77/263 - (29%)
• Similarity: 115/263 - (43%)
• Gaps: 57/263 - (21%)

  Fly    59 GENQSPIDLIFEDSKIVAIPRLRFNNYDQPLQ---------TPLVITNNGHTANMVIPQTRGGQR 114
            |:|||||:|..:|.:           :|..||         :...|.|||.|..:|...|  ..|
  Rat    25 GDNQSPIELHTKDIR-----------HDPSLQPWSVSYDPGSAKTILNNGKTCRVVFDDT--FDR 76

  Fly   115 PSINGSLLPGNFEAQSVHFHWGSREAKGSEHAINFQRYDVEMHIVHKNTIYETMGEATMHPDGLA 179
            ..:.|..|.|.:..:..|.||||.:..||||.::..:|..|:|:||.|..|.|.|||...|||:|
  Rat    77 SMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFGEALKQPDGIA 141

  Fly   180 VLGVMFRAVDRQTSQHY----GLNKI--------FNQLPRIVQYNSNATITGRLTVGQLLGNIVT 232
            |:|: |..:.|:..:..    .|:||        ||.......:.:                  .
  Rat   142 VVGI-FLKIGREKGEFQILLDALDKIKTKGKEAPFNHFDPSCLFPA------------------C 187

  Fly   233 GEFFTYNGSLTTPDCAEAVTWTVFPDVLDYPRRQITKLWNLRDSRQR----PLINNYRSIQDTNS 293
            .:::||:||.|||.|.|.:.|.:..:.:.....|:.||.:|..|.:.    ||:.|:|..|....
  Rat   188 RDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAENEPPVPLVGNWRPPQPIKG 252

  Fly   294 RDV 296
            |.|
  Rat   253 RVV 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH5	NP_001097988.2	Carb_anhydrase	50..299	CDD:459707	77/263 (29%)
Ca3	NP_062165.2	alpha_CA_I_II_III_XIII	1..259	CDD:239393	77/263 (29%)
		Involved in proton transfer. /evidence=ECO:0000250|UniProtKB:P07451	64..67		1/2 (50%)