Protein Alignment CAH5 and CA13

DIOPT Version :10

• Sequence 1: NP_001097988.2
• Gene: CAH5 / 50102
• FlyBaseID: FBgn0040629
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_940986.1
• Gene: CA13 / 377677
• HGNCID: 14914
• Length: 262
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 81/254 - (31%)
• Similarity: 123/254 - (48%)
• Gaps: 38/254 - (14%)

  Fly    59 GENQSPIDLIFEDSKIVAIPRLRFNNYDQPLQTPL----------VITNNGHTANMVIPQTRGGQ 113
            |:.||||::..::.|           ||..|: ||          :|:|:||:.|:....|.  .
Human    26 GDQQSPIEIKTKEVK-----------YDSSLR-PLSIKYDPSSAKIISNSGHSFNVDFDDTE--N 76

  Fly   114 RPSINGSLLPGNFEAQSVHFHWGSREAKGSEHAINFQRYDVEMHIVHKNT-IYETMGEATMHPDG 177
            :..:.|..|.|::..:.||.||||.:..||||.::...|..|:|:||.|: .|.:..||...|||
Human    77 KSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDG 141

  Fly   178 LAVLGVMFRAVDRQTSQHYGLNKIFNQLPRIVQYNSNATITGRLTVGQLLGNI-VTGEFFTYNGS 241
            |||||| |..:....||   |.||.:.|..|.:.....    |.|...||..: .:.:::||.||
Human   142 LAVLGV-FLQIGEPNSQ---LQKITDTLDSIKEKGKQT----RFTNFDLLSLLPPSWDYWTYPGS 198

  Fly   242 LTTPDCAEAVTWTVFPDVLDYPRRQITKLWNLRDSRQRP----LINNYRSIQDTNSRDV 296
            ||.|...|:|||.|....::...:|:.|..:|..:.:..    |::|:|..|....|.|
Human   199 LTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKV 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH5	NP_001097988.2	Carb_anhydrase	50..299	CDD:459707	81/254 (32%)
CA13	NP_940986.1	alpha_CA_I_II_III_XIII	2..261	CDD:239393	81/254 (32%)