Protein Alignment CAH5 and Car3

DIOPT Version :10

• Sequence 1: NP_001097988.2
• Gene: CAH5 / 50102
• FlyBaseID: FBgn0040629
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_031632.2
• Gene: Car3 / 12350
• MGIID: 88270
• Length: 260
• Species: Mus musculus
• Alignment Length: 274
• Identity: 83/274 - (30%)
• Similarity: 121/274 - (44%)
• Gaps: 37/274 - (13%)

  Fly    40 AGEYNYDEQG--DDW--TGTCQSGENQSPIDLIFEDSKIVAIPRLRFNNYDQPLQ---------T 91
            |.|:.|....  |.|  ......|:|||||:|..:|.|           :|..||         :
Mouse     2 AKEWGYASHNGPDHWHELYPIAKGDNQSPIELHTKDIK-----------HDPSLQPWSASYDPGS 55

  Fly    92 PLVITNNGHTANMVIPQTRGGQRPSINGSLLPGNFEAQSVHFHWGSREAKGSEHAINFQRYDVEM 156
            ...|.|||.|..:|...|.  .|..:.|..|.|.:..:..|.||||.:..||||.::..:|..|:
Mouse    56 AKTILNNGKTCRVVFDDTY--DRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAEL 118

  Fly   157 HIVHKNTIYETMGEATMHPDGLAVLGVMFRAVDRQTSQHYGLNKIFNQLPRIVQYNSNATITGRL 221
            |:||.|..|.|.|||...|||:||:|: |..:.|:..:   ...:.:.|.:|......|..| ..
Mouse   119 HLVHWNPKYNTFGEALKQPDGIAVVGI-FLKIGREKGE---FQILLDALDKIKTKGKEAPFT-HF 178

  Fly   222 TVGQLLGNIVTGEFFTYNGSLTTPDCAEAVTWTVFPDVLDYPRRQITKLWNLRDSRQR----PLI 282
            ....|..  ...:::||:||.|||.|.|.:.|.:..:.:.....|:.||.:|..|.:.    ||:
Mouse   179 DPSCLFP--ACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFSSAENEPPVPLV 241

  Fly   283 NNYRSIQDTNSRDV 296
            .|:|..|....|.|
Mouse   242 GNWRPPQPVKGRVV 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH5	NP_001097988.2	Carb_anhydrase	50..299	CDD:459707	80/262 (31%)
Car3	NP_031632.2	alpha_CA_I_II_III_XIII	1..259	CDD:239393	83/274 (30%)
		Involved in proton transfer. /evidence=ECO:0000250|UniProtKB:P07451	64..67		1/2 (50%)