DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH16 and ACA5

DIOPT Version :9

Sequence 1:	NP_001287620.1	Gene:	CAH16 / 50101	FlyBaseID:	FBgn0040628	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_172285.2	Gene:	ACA5 / 837324	AraportID:	AT1G08065	Length:	277	Species:	Arabidopsis thaliana

Alignment Length:	284	Identity:	73/284 - (25%)
Similarity:	112/284 - (39%)	Gaps:	81/284 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 EWNYLKNGK-----------DWEDLCSSGKHQSPI-LLDSRTARKWVLPGITFWHYYRLLKRPFY 77
            ::||.|.|:           :|. :|..|..|||| |.|.|         :...|....|:..:.
plant    34 QFNYEKKGEKGPENWGRLKPEWA-MCGKGNMQSPIDLTDKR---------VLIDHNLGYLRSQYL 88

  Fly    78 -----IRNNGHSISL-------DIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYKSRGSEHLI 130
                 |:|.||.|.:       .:.:|.||.:           |....:|:|      ..|||.:
plant    89 PSNATIKNRGHDIMMKFEGGNAGLGITINGTE-----------YKLQQIHWH------SPSEHTL 136

  Fly   131 NKRRFDAEIHIVHRNEKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRLMEAVVRVP--- 192
            |.:||..|.|:||:::..||           ||||....:.:.|....| |.|.::.:....
plant   137 NGKRFVLEEHMVHQSKDGRN-----------AVVAFFYKLGKPDYFLLT-LERYLKRITDTHESQ 189

  Fly   193 --IEDSNATVFGQSSLDQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSKFWL 255
              :|..:...||..|          :.::.:.||||||.|.|.|.|.:..|..|||:..:.   :
plant   190 EFVEMVHPRTFGFES----------KHYYRFIGSLTTPPCSENVIWTISKEMRTVTLKQLI---M 241

  Fly   256 LRDHWGHRLINNYRIVQDLNNRTV 279
            ||.....:..:|.|.:|..|.|.|
plant   242 LRVTVHDQSNSNARPLQRKNERPV 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	26..278	CDD:215000	71/280 (25%)
ACA5	NP_172285.2	PLN02179	9..231	CDD:177835	61/245 (25%)
ACA5	NP_172285.2	alpha_CA_prokaryotic_like	44..265	CDD:239398	68/272 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2610
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I2251
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm1014
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.770