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Protein Alignment CAH16 and CA12

DIOPT Version :9

Sequence 1:	NP_001287620.1	Gene:	CAH16 / 50101	FlyBaseID:	FBgn0040628	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_001209.1	Gene:	CA12 / 771	HGNCID:	1371	Length:	354	Species:	Homo sapiens

Alignment Length:	291	Identity:	88/291 - (30%)
Similarity:	141/291 - (48%)	Gaps:	34/291 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLLLPLAFYQST----NGMEWNYLKNGKDWEDLCS------SGKHQSPILLDSRTAR-KWVLPG 62
            :|||:.|....|:    ||.:|.|.  |.|.|:..|      .|..||||.|.|...: ...|..
Human    11 VLLLVILKEQPSSPAPVNGSKWTYF--GPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTP 73

  Fly    63 ITFWHYYRLLKRPFYIRNNGHSISLDIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYKS-RGS 126
            :.|..|.....:.|.:.|||||:.|::|...:     |.|  |:.||.|..||.|||:... .||
Human    74 LEFQGYNLSANKQFLLTNNGHSVKLNLPSDMH-----IQG--LQSRYSATQLHLHWGNPNDPHGS 131

  Fly   127 EHLINKRRFDAEIHIVHRN-EKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRLMEAVVR 190
            ||.::.:.|.||:||||.| :.|.:.:.|..:.:||||:|:::.:    .:.:....::...:..
Human   132 EHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEM----GSFNPSYDKIFSHLQH 192

  Fly   191 VPIEDSNATVFGQSSLDQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSKFWL 255
            |..:...|.|.| .::::|:...: .:::.|.||||||.|:.||.|.||.....::...:.....
Human   193 VKYKGQEAFVPG-FNIEELLPERT-AEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALET 255

  Fly   256 ------LRDHWGHRLINNYRIVQDLNNRTVF 280
                  :.|.....:|||:|.||..:.|.|:
Human   256 ALYCTHMDDPSPREMINNFRQVQKFDERLVY 286

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.