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Protein Alignment CAH16 and CA9

DIOPT Version :9

Sequence 1:	NP_001287620.1	Gene:	CAH16 / 50101	FlyBaseID:	FBgn0040628	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_001207.2	Gene:	CA9 / 768	HGNCID:	1383	Length:	459	Species:	Homo sapiens

Alignment Length:	272	Identity:	91/272 - (33%)
Similarity:	129/272 - (47%)	Gaps:	44/272 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 WNYLKNGKD--WEDL--CSSGKHQSPILLDSRTA------RKWVLPGITFWHYYRLLKRP-FYIR 79
            |.|   |.|  |..:  ..:|:.|||:.:..:.|      |...|.|      ::|...| ..:|
Human   141 WRY---GGDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPLELLG------FQLPPLPELRLR 196

  Fly    80 NNGHSISLDIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYKSRGSEHLINKRRFDAEIHIVHR 144
            |||||:.|.:|   .|.:..:..||   .|.|..||.|||:....||||.:...||.||||:||.
Human   197 NNGHSVQLTLP---PGLEMALGPGR---EYRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHVVHL 255

  Fly   145 NEKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRLMEAVVRVPIEDSNATVFGQSSLDQL 209
            :..:..:.:|:.:..||||:|   |.:.:...:::...:|:..:..:..|.|...|.|   ||
Human   256 STAFARVDEALGRPGGLAVLA---AFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPG---LD-- 312

  Fly   210 IGGVSHRDF---FTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSKFWLLRDH-WG---HRLINN 267
            |..:...||   |.||||||||.|.:.|.|.||.:|   .|.|..:...|.|. ||   .||..|
Human   313 ISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQT---VMLSAKQLHTLSDTLWGPGDSRLQLN 374

  Fly   268 YRIVQDLNNRTV 279
            :|..|.||.|.:
Human   375 FRATQPLNGRVI 386

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.