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Protein Alignment CAH16 and CA2

DIOPT Version :9

Sequence 1:	NP_001287620.1	Gene:	CAH16 / 50101	FlyBaseID:	FBgn0040628	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_000058.1	Gene:	CA2 / 760	HGNCID:	1373	Length:	260	Species:	Homo sapiens

Alignment Length:	275	Identity:	90/275 - (32%)
Similarity:	138/275 - (50%)	Gaps:	45/275 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 WNYLK-NGKD-W-EDL-CSSGKHQSPILLDSRTARKWVLPGITFWHYYRLLK---------RPFY 77
            |.|.| ||.: | :|. .:.|:.|||:.:|:.||:           |...||         ....
Human     5 WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAK-----------YDPSLKPLSVSYDQATSLR 58

  Fly    78 IRNNGHSISLDIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYKSRGSEHLINKRRFDAEIHIV 142
            |.||||:.:::...:.:  |..:.||.|.|.|.....||||||...:||||.::|:::.||:|:|
Human    59 ILNNGHAFNVEFDDSQD--KAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLV 121

  Fly   143 HRNEKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRLMEAVVRVPIEDSNA--TVFGQSS 205
            |.|.||.:..:||:|.|||||:.|.:    |..:....|.::::.:..:..:..:|  |.|....
Human   122 HWNTKYGDFGKAVQQPDGLAVLGIFL----KVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRG 182

  Fly   206 L--DQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSKFWLLRDHW----GHRL 264
            |  :.|       |::||.||||||...|.|||||..|..:|:...|.||..|..:.    ...:
Human   183 LLPESL-------DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240

  Fly   265 INNYRIVQDLNNRTV 279
            ::|:|..|.|.||.:
Human   241 VDNWRPAQPLKNRQI 255

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.