DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH16 and ca16b

DIOPT Version :9

Sequence 1:	NP_001287620.1	Gene:	CAH16 / 50101	FlyBaseID:	FBgn0040628	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	XP_001919055.3	Gene:	ca16b / 569183	ZFINID:	ZDB-GENE-080818-1	Length:	1382	Species:	Danio rerio

Alignment Length:	248	Identity:	69/248 - (27%)
Similarity:	126/248 - (50%)	Gaps:	20/248 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 KHQSPI-LLDSRTARKWVLPGITFWHYYRLLKRPFYIRNNGHSISLDIPVTSNGRKPFITGGRLK 106
            ::|||: :||..|........:|...:.........::|.|.::|:   |..|..  |:.|..|.
Zfish    76 RNQSPVDILDPETQVSQECQELTLDGFETKSSNRTTMKNTGKTVSI---VLKNDY--FVRGAGLP 135

  Fly   107 GRYYADGLHFHWGSYK-SRGSEHLINKRRFDAEIHI-VHRNEKYRNIAQAVRQKDGLAVVAIMVA 169
            ||:.|:.:.|||||.. |.||||.||.::|..|:.| .:.::.:.:::.|::::..:|.:|:...
Zfish   136 GRFKAEKVEFHWGSTNGSAGSEHSINGKKFPVEMQIYFYNSDDFDSLSTAIKERRIIAAMAVFFQ 200

  Fly   170 IVRKDNAKSTPLSRLMEAVVRVPIEDSNATVFGQSSLDQLIGGVSHRDFFTYEGSLTTPLCDETV 234
            :..|||..:.|:...::.||....|.:..:...:..|...:|     .::.|.||||||.|.:.|
Zfish   201 VATKDNIAAEPIIAGLKRVVHHEKETNLGSFILRDLLPSSLG-----SYYRYTGSLTTPPCSKVV 260

  Fly   235 TWIVFTETTTVTMSSVSKFWLL-----RDHWG--HRLINNYRIVQDLNNRTVF 280
            .||:|:....::...:..|:.:     :||..  ..|.||:|.:|||::|.:|
Zfish   261 EWIIFSRPVYLSYHQLEAFYSIFTTEQQDHVKSVDYLRNNHRPIQDLDSRRIF 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	26..278	CDD:215000	67/244 (27%)
ca16b	XP_001919055.3	alpha_CARP_receptor_like	62..314	CDD:239396	69/248 (28%)
		FN3	340..417	CDD:214495
		Herpes_BLLF1	450..>557	CDD:330317
		PTPc	790..1057	CDD:214550
		PTPc	1089..1347	CDD:214550
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810