DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CAH16 and ca4a

DIOPT Version :9

Sequence 1:	NP_001287620.1	Gene:	CAH16 / 50101	FlyBaseID:	FBgn0040628	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_001107879.2	Gene:	ca4a / 555196	ZFINID:	ZDB-GENE-080204-85	Length:	306	Species:	Danio rerio

Alignment Length:	283	Identity:	88/283 - (31%)
Similarity:	134/283 - (47%)	Gaps:	27/283 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLPLAFYQSTNGMEWNY---------LKNGKDWEDL-CSSGK-HQSPI-LLDSRTARKWVLPGIT 64
            ||||..:..| |.:|.|         .|..:.|.:: ...|| .|||| ::..:|.....|....
Zfish     9 LLPLILHACT-GADWCYQTQVSCDSHCKGPEKWREVNADCGKDRQSPINIVTKQTKLDERLTPFR 72

  Fly    65 FWHYYRLLKRPFYIRNNGHSISLDIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYKSRGSEHL 129
            |..|..:....  ::|||||:.:.|||.:.     |:||.|...|.|...|.|||.....||||.
Zfish    73 FTGYQTVFDGT--LKNNGHSVQVSIPVPAT-----ISGGNLAEPYKAVQFHLHWGISSGPGSEHT 130

  Fly   130 INKRRFDAEIHIVHRNEKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRLMEAVVRVPIE 194
            |:..::..|:||||..:||..|..|::...|:||:.....:....|.|....:..:.:|     :
Zfish   131 IDGEQYPMELHIVHMKQKYIRIEDALKDPSGVAVLGFFYEVSSTTNRKYDLFAHALRSV-----Q 190

  Fly   195 DSNA-TVFGQSSLDQLI-GGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSKFWLLR 257
            ::|. |...:.||:||| ..|:..:::.|:||||||.|.|.|.|.||.:...:....:..|..|:
Zfish   191 NTNGNTTLRKISLNQLILPEVNMTNYYRYDGSLTTPGCTEAVVWTVFEKPIPLDSEQLQAFSSLK 255

  Fly   258 DHWGHRLINNYRIVQDLNNRTVF 280
            ...|..::..:|.||..|.|.|:
Zfish   256 FRDGKPMVGTFRPVQPRNGRVVY 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	26..278	CDD:215000	80/265 (30%)
ca4a	NP_001107879.2	alpha_CA_IV_XV_like	49..279	CDD:239391	77/242 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	157	1.000	Domainoid score	I4112
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	159	1.000	Inparanoid score	I4224
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm6335
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	1	1.100	-	-	O	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.830