DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH16 and CAH6

DIOPT Version :9

Sequence 1:	NP_001287620.1	Gene:	CAH16 / 50101	FlyBaseID:	FBgn0040628	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_001097987.1	Gene:	CAH6 / 43701	FlyBaseID:	FBgn0039838	Length:	298	Species:	Drosophila melanogaster

Alignment Length:	286	Identity:	151/286 - (52%)
Similarity:	200/286 - (69%)	Gaps:	4/286 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAIAFHKLLLLLPLAFYQSTNG----MEWNYLKNGKDWEDLCSSGKHQSPILLDSRTARKWVLP 61
            ||..||||||||||||:..::|.    ..|:|..||::|..:||:|:.||||.|:.:.:....||
  Fly     1 MQPNAFHKLLLLLPLAYQHTSNDHKDESHWDYETNGQNWGGICSTGERQSPISLNVQKSLIVPLP 65

  Fly    62 GITFWHYYRLLKRPFYIRNNGHSISLDIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYKSRGS 126
            .|.|.:|...|:.|..:.||||:..::||.|:||.|||||||.||||:.|:..||||||..||||
  Fly    66 RIVFGNYDVKLRGPLTLLNNGHTAHVEIPETANGNKPFITGGLLKGRFVAEAFHFHWGSPSSRGS 130

  Fly   127 EHLINKRRFDAEIHIVHRNEKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRLMEAVVRV 191
            ||.||::|||.|:|||||||||.:|.:|..:|||:||:.:|:.||:..|.....||::|.|:.||
  Fly   131 EHSINQQRFDVEMHIVHRNEKYGDIDEAKNKKDGIAVIGVMLKIVKNPNRIFPGLSKVMSALPRV 195

  Fly   192 PIEDSNATVFGQSSLDQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSKFWLL 256
            ...::..|:.|..||.|::|.|:.||||||.||||||||:::|||.||::...|..|||||||.|
  Fly   196 TKYNAKTTIPGGLSLGQMLGNVNPRDFFTYRGSLTTPLCEQSVTWTVFSQVLPVPYSSVSKFWKL 260

  Fly   257 RDHWGHRLINNYRIVQDLNNRTVFYK 282
            ||..|||||||:|.:|..|.|.|||:
  Fly   261 RDSEGHRLINNFRDIQPRNGRPVFYR 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	26..278	CDD:215000	132/251 (53%)
CAH6	NP_001097987.1	Carb_anhydrase	30..282	CDD:215000	132/251 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450174
Domainoid	1	1.000	91	1.000	Domainoid score	I2610
eggNOG	1	0.900	-	-		E1_COG3338
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I2251
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D113047at6656
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm6335
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	1	1.100	-	-	P	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
	11	10.800