DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH16 and CAH9

DIOPT Version :9

Sequence 1:	NP_001287620.1	Gene:	CAH16 / 50101	FlyBaseID:	FBgn0040628	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_651535.1	Gene:	CAH9 / 43264	FlyBaseID:	FBgn0039486	Length:	311	Species:	Drosophila melanogaster

Alignment Length:	291	Identity:	106/291 - (36%)
Similarity:	158/291 - (54%)	Gaps:	18/291 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAIAFHKLLLLLPLAFYQSTNGMEWNYLK-NGKDW---EDLCSSGKHQSPILLDSRTARKWVLP 61
            |:..||.:...|| :.:.|:.:...:.|.: |.:.|   ...| :||.||||.:.:.......:|
  Fly     1 MKLTAFLEASFLL-ICWSQAVSSHVFGYSEPNQRRWARHHGHC-AGKTQSPIAITTSRTTAIHMP 63

  Fly    62 GITFWHYYRLLKRPFYIRNNGHSISLDIP---VTSNGRK--PFITGGRLKGRYYADGLHFHWGSY 121
            .:....|:.||..|..:.||||::|:.||   ||..|..  |:|.|.:|.|.:..:|||||||..
  Fly    64 AVDMIGYHNLLPYPLKMINNGHTVSITIPKVNVTEVGEDFLPYIRGAKLPGEFEVEGLHFHWGDK 128

  Fly   122 KSRGSEHLINKRRFDAEIHIVHRNEKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRLME 186
            .:|||||:||..|:..|:||||||:||..|.:|:...||.||:.....:...:.|....::|.:.
  Fly   129 NNRGSEHVINDIRYTMEMHIVHRNKKYATIGEALNHPDGAAVLGFFFNLDEDEGAGLVTINRHLH 193

  Fly   187 AVVRVPIEDSN--ATVFGQSSLDQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSS 249
            .     |.|:|  ||:....||..||.||....|:||:||||||.|.|.||||:|.:...::...
  Fly   194 L-----IADANQEATLNVTFSLSSLIAGVDVDKFYTYKGSLTTPPCSEAVTWILFPDPIPISPKQ 253

  Fly   250 VSKFWLLRDHWGHRLINNYRIVQDLNNRTVF 280
            :|:|..|.|.....|::|:|.:|.:.||.:|
  Fly   254 ISRFRQLSDTQDGALVDNFRTLQPVGNRRIF 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	26..278	CDD:215000	98/262 (37%)
CAH9	NP_651535.1	Carb_anhydrase	25..282	CDD:215000	98/262 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450182
Domainoid	1	1.000	91	1.000	Domainoid score	I2610
eggNOG	1	0.900	-	-		E1_COG3338
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I2251
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D113047at6656
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm6335
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	1	1.100	-	-	P	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
	11	10.800