DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH16 and CAH7

DIOPT Version :9

Sequence 1:	NP_001287620.1	Gene:	CAH16 / 50101	FlyBaseID:	FBgn0040628	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_001287267.1	Gene:	CAH7 / 41238	FlyBaseID:	FBgn0037788	Length:	304	Species:	Drosophila melanogaster

Alignment Length:	268	Identity:	102/268 - (38%)
Similarity:	137/268 - (51%)	Gaps:	32/268 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 EWNY--LKNGKD-----WEDLCSSGKHQSPILLDSRTARKWVLPGITFWHYYRLLKRPFYIRNNG 82
            ||.|  |.|.:|     |..||.|||.||||.|..:.|.|.....:.|.:|....|. ..:.|||
  Fly    21 EWGYPDLDNNQDEPFPKWGGLCDSGKKQSPINLHVKGALKGEFDALKFENYDEHQKN-LRMVNNG 84

  Fly    83 HSISL---DIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYKSRGSEHLINKRRFDAEIHIVHR 144
            |||.|   |..:|       ::||.|...:..:.:|.||      .|||.||..|:..|:|||||
  Fly    85 HSIQLSGFDHELT-------LSGGALLQDFVVEQIHMHW------WSEHTINDIRYPLEVHIVHR 136

  Fly   145 NEKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRLMEAVVRVPIEDS-NATVFGQSSL-- 206
            |..|.|:..|...|||:.|:.::..:   .|..:..:..:::::..|...|| |..|....||
  Fly   137 NTIYPNMTMAANFKDGIVVIGVLYHV---SNTPNEAIGSIIKSLGAVKSYDSMNKPVLVADSLAV 198

  Fly   207 DQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSKFWLLRDHWGHRLINNYRIV 271
            |.|:..|  .::|||.||||||.|.|.|||||.|||..||:..|::|..:....|.:|.||||.:
  Fly   199 DDLVPSV--ENYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQVNEFKEIEYDEGKQLHNNYREL 261

  Fly   272 QDLNNRTV 279
            |..|||.|
  Fly   262 QSENNRAV 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	26..278	CDD:215000	99/264 (38%)
CAH7	NP_001287267.1	alpha_CA	45..269	CDD:238200	91/242 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446794
Domainoid	1	1.000	91	1.000	Domainoid score	I2610
eggNOG	1	0.900	-	-		E1_COG3338
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I2251
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D113047at6656
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm1014
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	1	1.100	-	-	P	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
	11	10.800