DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH16 and Car15

DIOPT Version :9

Sequence 1:	NP_001287620.1	Gene:	CAH16 / 50101	FlyBaseID:	FBgn0040628	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_001099371.1	Gene:	Car15 / 288360	RGDID:	1306018	Length:	323	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	90/296 - (30%)
Similarity:	143/296 - (48%)	Gaps:	25/296 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAIAFHKLLLLLPLAFYQSTNGMEWNYLKNGKD-------WEDLCSS--GKHQSPILLDSR-TA 55
            |.|:.| :|..||.||....:|| .|.|  :.:|       |::|..:  |..|||:.:|.| ..
  Rat     1 MWALGF-RLCFLLMLAAQVDSNG-TWCY--DSQDPKCGPAHWKELAPACGGPTQSPVNIDLRLVQ 61

  Fly    56 RKWVLPGITFWHYYRLLKRPFYIRNNGHSISLDIPVTSNGRKPFITGGRL-KGRYYADGLHFHWG 119
            |.:.|....|..|....:.|:.:.|:||::.|.:. :.....|.|.|..| ...|....||||||
  Rat    62 RDYALKPFIFHGYDSAPQDPWILENDGHTVLLRVH-SCQQNCPAIRGAGLPSSEYRLLQLHFHWG 125

  Fly   120 SYKSRGSEHLINKRRFDAEIHIVHRNEKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRL 184
            |...:||||.::::....|:|:||.|.||:::..|..|.||||::|:::....|||...:.:...
  Rat   126 SPGHKGSEHSVDEKHGSMEMHMVHMNTKYQSMGHARSQPDGLAILAVLLVEEDKDNTNFSAIVSG 190

  Fly   185 MEAVVRVPIEDSNATVFGQSSLDQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSS 249
            ::.|....:..:..:.|..:||  |...:....::.|.||||||.|:..|.|.||..|..:..:.
  Rat   191 LKNVSSPGVSVNLTSTFALASL--LPSALGLLRYYRYSGSLTTPGCEPAVLWTVFENTVPIGHAQ 253

  Fly   250 VSKFWLLRD------HWGHRLINNYRIVQDLNNRTV 279
            |.:|..:..      | ...|.:|:|..|.|..|.:
  Rat   254 VVQFQAVPQTGPPGLH-PRPLTDNFRPQQPLGGRRI 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	26..278	CDD:215000	79/268 (29%)
Car15	NP_001099371.1	alpha_CA_IV_XV_like	47..290	CDD:239391	75/246 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18952
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110