Protein Alignment CAH16 and CA14

DIOPT Version :9

• Sequence 1: NP_001287620.1
• Gene: CAH16 / 50101
• FlyBaseID: FBgn0040628
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_036245.1
• Gene: CA14 / 23632
• HGNCID: 1372
• Length: 337
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 94/286 - (32%)
• Similarity: 136/286 - (47%)
• Gaps: 31/286 - (10%)

  Fly    10 LLLLPLAFYQSTNGMEWNYL-KNGKD-WE---DLCSSGKHQSPILL--DSRTARKWVLPGITFWH 67
            |||..:....:..|..|.|. .:|:| |.   ..|.:.. ||||.:  ||.|... .||.:....
Human     6 LLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNA-QSPIDIQTDSVTFDP-DLPALQPHG 68

  Fly    68 YYRLLKRPFYIRNNGHSISLDIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYKS-RGSEHLIN 131
            |.:....|..:.||||::.|.:|.|      ...|| |..:|.|..||.|||...| .||||.||
Human    69 YDQPGTEPLDLHNNGHTVQLSLPST------LYLGG-LPRKYVAAQLHLHWGQKGSPGGSEHQIN 126

  Fly   132 KRRFDAEIHIVH-RNEKYRNIAQAVRQKDGLAVVAIMVAIVRKDN-AKSTPLSRLMEAVVRVPIE 194
            .....||:|||| .::.|.::::|..:..||||:.|::.:....| |....||.|.|  ||...:
Human   127 SEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHE--VRHKDQ 189

  Fly   195 DSNATVFG-QSSLDQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSK----FW 254
            .::...|. :..|.:.:|     .:|.|.||||||.|.::|.|.||...:.::|..:.|    .:
Human   190 KTSVPPFNLRELLPKQLG-----QYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLF 249

  Fly   255 LLRDHWGHRLINNYRIVQDLNNRTVF 280
            ...:.....|:.|||.:|.||.|.||
Human   250 STEEEPSKLLVQNYRALQPLNQRMVF 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	26..278	CDD:215000	87/266 (33%)
CA14	NP_036245.1	alpha_CA_XII_XIV	29..278	CDD:239400	88/263 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.720