DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mask and SKOR

DIOPT Version :9

Sequence 1:	NP_001247280.1	Gene:	mask / 50070	FlyBaseID:	FBgn0043884	Length:	4010	Species:	Drosophila melanogaster
Sequence 2:	NP_186934.1	Gene:	SKOR / 821052	AraportID:	AT3G02850	Length:	828	Species:	Arabidopsis thaliana

Alignment Length:	668	Identity:	145/668 - (21%)
Similarity:	232/668 - (34%)	Gaps:	223/668 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  2180 CPPT--CVQHQVATQTHPASVVVPQPAVGYTQF-ALQASQQQQMQQNELSIW------------P 2229
            |..|  |:.:.:|| |.|||      ..|||.. :|:.......:..|:.:|            .
plant   228 CTHTAACIFYYLAT-TLPAS------QEGYTWIGSLKLGDYSYSKFREIDLWTRYTTSMYFAVVT 285

  Fly  2230 MATPTPAPSSGVSSTKSMPG---------------GIAKKAIDKQSRKERRCVVRQTPAGI---Q 2276
            |||........|:..:.:..               |.....|.|.|:.||   .|...|.|   .
plant   286 MATVGYGDIHAVNMREMIFAMVYISFDMILGAYLIGNMTALIVKGSKTER---FRDKMADIMRYM 347

  Fly  2277 ENTKL----------HLQPQVATAQQQFLVQNQLAVATTVSLDKTI------------------- 2312
            ...||          ||:.|..::..:..|...:.|:....:.:|:
plant   348 NRNKLGRNIRGQITGHLRLQYESSYTEAAVLQDIPVSIRAKIAQTLYLPYIEKVPLFRGCSSEFI 412

  Fly  2313 ---------------EIDSETESNHDTALTLACAG----------GHEELVELL----------- 2341
                           |:..|..|..| .|...|.|          |.||:|.:|
plant   413 NQIVIRLHEEFFLPGEVIMEQGSVVD-QLYFVCHGVLEEIGITKDGSEEIVAVLQPDHSFGEISI 476

  Fly  2342 -----------INRGANIEHRDKKGFTPLILAATAGHD--KVVDILL--KHS----AELEAQ--- 2384
                       :.....|...||:.|..::  ....||  ::::.||  |.|    .:||:.
plant   477 LCNIPQPYTVRVAELCRILRLDKQSFMNIL--EIFFHDGRRILNNLLEGKESNVRIKQLESDITF 539

  Fly  2385 --SERTKDTPLSL---ACSGGRYEVVELLLSVGANKEHRNVSDY---TPLSLAASGGYVNIIKLL 2441
              |::..:..|.|   |..|..|::..|:.:.|    ..|.:||   :||.||||.||.:|...|
plant   540 HISKQEAELALKLNSAAFYGDLYQLKSLIRAGG----DPNKTDYDGRSPLHLAASRGYEDITLYL 600

  Fly  2442 LSHGAEINSRTGSKLGISPLMLAAMNGHTPAVKLLLDQGSDINAQIETNRNTALTLACFQGRHEV 2506
            :....::|.:  .|||.:||:.|..||:.....||:.:|:.:|.:   |..|.|.....:|..:.
plant   601 IQESVDVNIK--DKLGSTPLLEAIKNGNDRVAALLVKEGATLNIE---NAGTFLCTVVAKGDSDF 660

  Fly  2507 VSLLLDRRANVEHRAKTGLTPLMEAASGGYIEVGRVLLDKGADVNAAPVPTSRD----TALTIAA 2567
            :                                 :.||..|.|      |.|:|    |.|.:||
plant   661 L---------------------------------KRLLSNGID------PNSKDYDHRTPLHVAA 686

  Fly  2568 DKGHQKFVELLLSRNASVEVKNKKGNSPLWLAAHGGHLSVVELLYDHNADIDSQDNRRVSCLMAA 2632
            .:|.......|:..:|:|..|::.||:||..|...|:..:::||.|       ..|.::|...:.
plant   687 SEGFYVLAIQLVEASANVLAKDRWGNTPLDEALGCGNKMLIKLLED-------AKNSQISSFPSG 744

  Fly  2633 FRKGHTKIVKWMVQYVSQFPSDQEMIRFIGTI-----SDKELIDKCFDCMKILRSAK------EA 2686
            .::...|:.|.........|.|.:..|..|.:     |.:|||          |:||      ||
plant   745 SKEPKDKVYKKKCTVYFSHPGDSKEKRRRGIVLWVPRSIEELI----------RTAKEQLNVPEA 799

  Fly  2687 QAVKANKNASILLEELDL 2704
            ..|.:...|.|:  ::||
plant   800 SCVLSEDEAKII--DVDL 815

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mask	NP_001247280.1	ANK	555..684	CDD:238125
		Ank_2	564..659	CDD:289560
		ANK repeat	596..628	CDD:293786
		ANK	633..751	CDD:238125
		ANK repeat	633..661	CDD:293786
		Ank_2	635..724	CDD:289560
		ANK repeat	663..694	CDD:293786
		ANK repeat	696..724	CDD:293786
		Ank_5	716..771	CDD:290568
		ANK	726..850	CDD:238125
		ANK repeat	730..760	CDD:293786
		ANK repeat	765..794	CDD:293786
		Ank_2	768..859	CDD:289560
		ANK repeat	796..827	CDD:293786
		ANK repeat	829..858	CDD:293786
		ANK repeat	862..894	CDD:293786
		ANK	896..1014	CDD:238125
		ANK repeat	896..923	CDD:293786
		Ank_2	898..989	CDD:289560
		ANK repeat	927..957	CDD:293786
		ANK repeat	959..991	CDD:293786
		ANK	989..>1049	CDD:238125
		ANK repeat	993..1023	CDD:293786
		Ank_4	995..1046	CDD:290365
		ANK	2321..2349	CDD:197603	9/59 (15%)
		ANK repeat	2323..2352	CDD:293786	10/60 (17%)
		Ank_2	2326..2419	CDD:289560	28/140 (20%)
		ANK	2350..2477	CDD:238125	42/145 (29%)
		ANK repeat	2354..2386	CDD:293786	9/44 (20%)
		ANK repeat	2390..2419	CDD:293786	7/31 (23%)
		Ank_2	2393..2486	CDD:289560	33/98 (34%)
		ANK repeat	2421..2452	CDD:293786	13/33 (39%)
		ANK repeat	2456..2486	CDD:293786	11/29 (38%)
		ANK	2457..2579	CDD:238125	26/125 (21%)
		Ank_2	2461..2552	CDD:289560	16/90 (18%)
		ANK repeat	2492..2521	CDD:293786	3/28 (11%)
		ANK	2519..2645	CDD:238125	29/129 (22%)
		ANK repeat	2523..2589	CDD:293786	15/69 (22%)
		Ank_2	2528..2622	CDD:289560	25/97 (26%)
		ANK repeat	2560..2587	CDD:293786	9/30 (30%)
		ANK repeat	2591..2622	CDD:293786	9/30 (30%)
		KH-I	3049..3110	CDD:238053
SKOR	NP_186934.1	PLN03192	70..827	CDD:215625	145/668 (22%)
		ANK repeat	580..611	CDD:293786	11/32 (34%)
		ANK repeat	613..644	CDD:293786	11/33 (33%)
		ANK repeat	677..708	CDD:293786	8/30 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000