DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment mask and TPR10

DIOPT Version :9

Sequence 1:NP_001247280.1 Gene:mask / 50070 FlyBaseID:FBgn0043884 Length:4010 Species:Drosophila melanogaster
Sequence 2:NP_001189808.1 Gene:TPR10 / 819629 AraportID:AT3G04710 Length:680 Species:Arabidopsis thaliana


Alignment Length:648 Identity:151/648 - (23%)
Similarity:246/648 - (37%) Gaps:156/648 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   542 KQALTKMRCA-----SSPRDKNGFSRSLVAACTDNDVN-----------TVKRLLCKG-NVNLND 589
            |.||.::|.|     :|.:.|:..|:.|....|..||.           ..|:||.|| :.||..
plant    14 KPALPEVRSAATTPVASQKPKHRLSKQLSMCETPRDVAWERRRRQMIMIQEKKLLHKGASDNLCI 78

  Fly   590 AAASTDDGESLLSMACSAGYYELAQVLLAMSAAQVEDKGQK--DSTPLMEAASAGHLDIVKL--- 649
            .|..||:..:.|..:...|:            ...|:.|||  ::.|.::...|.:..:..|   
plant    79 QANLTDEDLNELKGSIELGF------------GFNEEAGQKLCNTLPALDLYFAVNRQLSPLPSP 131

  Fly   650 LLNHNADVNAH-------CA---TGNTPLMFACAGGQVDVVKVLLKH------------------ 686
            ..:.::..:|.       |:   |.:..:...|.|.....:|..|:|                  
plant   132 SSSRSSSASASTFSYSIPCSPKKTDSDSVKILCPGDDPQQMKQRLRHWAQAVACSISDNQTDRHK 196

  Fly   687 -------GANVEEQNENGHTPLMEAASAGHVEVAKVLLEHGAGINTHSNEFKESALTLACYKGHL 744
                   |.|.:.||     ||..:.:.|.|..    :...|.....:.|..:..|..|| .|:|
plant   197 QTPVSTNGTNSDIQN-----PLQVSRTKGLVSA----MAPDASTALAAREKVQQILNAAC-TGNL 251

  Fly   745 DMVRFL---LQAGAD-----QEHKTDEMHTALMEASMDGHVEVARLLLDSGAQVNMPTDSFESPL 801
            :.::.:   |..|.|     :..|......||..|:.:|..|:.|.||:                
plant   252 EFLKNVAKQLDEGKDLTKTVESIKDANKRGALHFAAREGQTEICRYLLE---------------- 300

  Fly   802 TLAACGGHVELATLLIERGANIEEVNDEGYTPLMEAAREGHEEMVALLLSKGANINATTEETQET 866
                            |...|.:..::.|.|||:.|||:|..|.|..||.:||:.|..:      
plant   301 ----------------ELKLNADAKDETGDTPLVHAARQGQIETVKYLLEQGADPNIAS------ 343

  Fly   867 ALTLACCGGFMEVAAFLIKEGANLELGASTPLMEASQEGHTDLVSFLLKKKANVHAETQTGDTAL 931
                                    |||| |.|..|:..|..:|:..||.:...|.:|:::| |.|
plant   344 ------------------------ELGA-TALHHAAGTGEIELLKELLSRGVPVDSESESG-TPL 382

  Fly   932 THACENGHTDAAGVLLSYGAELEHESEGGRTPLMKACRAGHLCTVKFLIQKGANVNKQTTSNDHT 996
            ..|..:...:|..|||.:.|....|:|...|||:.|..||.|..::.|::.||..|  ..:...|
plant   383 IWAAGHDQKNAVEVLLEHNANPNAETEDNITPLLSAVAAGSLSCLELLVKAGAKAN--VFAGGAT 445

  Fly   997 ALSLACAGGHQSVVELLLKNNADPFHKLKDNSTMLIEASKGGHTRVVELLFRYPNISPTENAASA 1061
            .|.:|...|:..::..|||..|||..|.::.:..|..|:...:.:|||:||.......|.:..:.
plant   446 PLHIAADIGNLELINCLLKAGADPNQKDEEGNRPLEVAAARDNRKVVEILFPLTTKPETVSDWTV 510

  Fly  1062 NVTQAAPTSN-QPGPNQMRQKIMKQQLQHQLQQLNAPPGLHELSEAARASNQQHFHQQQFSSA 1123
            :...|...|| :...|..:.|..:..::..|..::  |.....:..|:|..|..||::.|..|
plant   511 DGILAHMESNKEQEENSNKAKSQETGIKKDLPVVS--PEAKAKAAEAKARGQDAFHRKDFQMA 571

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
maskNP_001247280.1 ANK 555..684 CDD:238125 31/155 (20%)
Ank_2 564..659 CDD:289560 23/111 (21%)
ANK repeat 596..628 CDD:293786 3/31 (10%)
ANK 633..751 CDD:238125 26/158 (16%)
ANK repeat 633..661 CDD:293786 4/37 (11%)
Ank_2 635..724 CDD:289560 19/126 (15%)
ANK repeat 663..694 CDD:293786 8/55 (15%)
ANK repeat 696..724 CDD:293786 5/27 (19%)
Ank_5 716..771 CDD:290568 13/62 (21%)
ANK 726..850 CDD:238125 30/131 (23%)
ANK repeat 730..760 CDD:293786 8/37 (22%)
ANK repeat 765..794 CDD:293786 8/28 (29%)
Ank_2 768..859 CDD:289560 24/90 (27%)
ANK repeat 796..827 CDD:293786 2/30 (7%)
ANK repeat 829..858 CDD:293786 14/28 (50%)
ANK repeat 862..894 CDD:293786 2/31 (6%)
ANK 896..1014 CDD:238125 35/117 (30%)
ANK repeat 896..923 CDD:293786 8/26 (31%)
Ank_2 898..989 CDD:289560 30/90 (33%)
ANK repeat 927..957 CDD:293786 9/29 (31%)
ANK repeat 959..991 CDD:293786 11/31 (35%)
ANK 989..>1049 CDD:238125 18/59 (31%)
ANK repeat 993..1023 CDD:293786 10/29 (34%)
Ank_4 995..1046 CDD:290365 16/50 (32%)
ANK 2321..2349 CDD:197603
ANK repeat 2323..2352 CDD:293786
Ank_2 2326..2419 CDD:289560
ANK 2350..2477 CDD:238125
ANK repeat 2354..2386 CDD:293786
ANK repeat 2390..2419 CDD:293786
Ank_2 2393..2486 CDD:289560
ANK repeat 2421..2452 CDD:293786
ANK repeat 2456..2486 CDD:293786
ANK 2457..2579 CDD:238125
Ank_2 2461..2552 CDD:289560
ANK repeat 2492..2521 CDD:293786
ANK 2519..2645 CDD:238125
ANK repeat 2523..2589 CDD:293786
Ank_2 2528..2622 CDD:289560
ANK repeat 2560..2587 CDD:293786
ANK repeat 2591..2622 CDD:293786
KH-I 3049..3110 CDD:238053
TPR10NP_001189808.1 DUF1685 82..>125 CDD:285215 10/54 (19%)
Alpha_adaptinC2 <202..264 CDD:296022 16/71 (23%)
Ank_2 245..341 CDD:289560 32/128 (25%)
ANK <245..299 CDD:295348 14/54 (26%)
ANK repeat 282..310 CDD:293786 10/59 (17%)
ANK 307..431 CDD:238125 46/155 (30%)
ANK repeat 313..343 CDD:293786 15/29 (52%)
Ank_2 317..407 CDD:289560 34/121 (28%)
ANK repeat 345..376 CDD:293786 11/31 (35%)
ANK repeat 378..407 CDD:293786 9/29 (31%)
ANK 380..495 CDD:238125 37/116 (32%)
Ank_2 382..473 CDD:289560 30/92 (33%)
ANK repeat 410..441 CDD:293786 11/32 (34%)
ANK repeat 442..473 CDD:293786 10/30 (33%)
TPR repeat 585..615 CDD:276809
TPR repeat 620..645 CDD:276809
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm2422
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

Return to query results.
Submit another query.