DRSC/TRiP Functional Genomics Resources

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Protein Alignment mask and Nfkbib

DIOPT Version :9

Sequence 1:NP_001247280.1 Gene:mask / 50070 FlyBaseID:FBgn0043884 Length:4010 Species:Drosophila melanogaster
Sequence 2:NP_110494.2 Gene:Nfkbib / 81525 RGDID:621887 Length:359 Species:Rattus norvegicus


Alignment Length:321 Identity:86/321 - (26%)
Similarity:116/321 - (36%) Gaps:67/321 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   794 TDSFESPLTLAACGGHVELATLLIERGANIEEV---NDEGYTPLMEAAREGHEEMVALLLSKGAN 855
            |:..::.|.||....|......|:...|..|.:   ||.|.|.|..||..|....|..|.:.||.
  Rat    55 TEDGDTALHLAVIHQHEPFLDFLLGFSAGTEYLDLQNDLGQTALHLAAILGEASTVEKLYAAGAG 119

  Fly   856 INATTEETQETALTLACCGGFMEVAAFLIKEGANLELGASTPLMEASQEGHTDLVSFLLKKKANV 920
            : ..||....|||.|||.......|..|::...:....||...:..||: ||...|         
  Rat   120 V-LVTERGGHTALHLACRVRAHTCAYVLLQPRPSHPRDASDTYLTQSQD-HTPDTS--------- 173

  Fly   921 HAETQTGDTALTHACENGHTDAAGVLLSYGAELEHESEGGRTPLMKACRAGHLCTVKFLIQKGAN 985
            ||...| |.......|....|.     .:..:||.|:..|.|||..|........|:.|...||:
  Rat   174 HAPVAT-DPQPNPGNEEELRDE-----DWRLQLEAENYDGHTPLHVAVIHKDAEMVQLLRDAGAD 232

  Fly   986 VNKQTTSNDHTALSLACAGGHQSVVELLLKNNADPFHKLKDNSTMLIEASKGGHTRVVELLFRYP 1050
            :||...:...|.|.||..|....|:.||||..|||..::           .||.|.:...|.| |
  Rat   233 LNKPEPTCGRTPLHLAVEGQAAGVLALLLKAGADPTARM-----------YGGRTPLGSALLR-P 285

  Fly  1051 N---------------------ISPTENAASAN--------------VTQAAPTSNQPGPN 1076
            |                     :||..|::|.:              |..:..:.|||.|:
  Rat   286 NPVLARLLRAHGAPEPEDEDDKLSPCSNSSSDSDSDNRDEGDEYDDIVVHSRRSQNQPPPS 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
maskNP_001247280.1 ANK 555..684 CDD:238125
Ank_2 564..659 CDD:289560
ANK repeat 596..628 CDD:293786
ANK 633..751 CDD:238125
ANK repeat 633..661 CDD:293786
Ank_2 635..724 CDD:289560
ANK repeat 663..694 CDD:293786
ANK repeat 696..724 CDD:293786
Ank_5 716..771 CDD:290568
ANK 726..850 CDD:238125 17/58 (29%)
ANK repeat 730..760 CDD:293786
ANK repeat 765..794 CDD:293786 86/321 (27%)
Ank_2 768..859 CDD:289560 20/67 (30%)
ANK repeat 796..827 CDD:293786 7/33 (21%)
ANK repeat 829..858 CDD:293786 10/28 (36%)
ANK repeat 862..894 CDD:293786 8/31 (26%)
ANK 896..1014 CDD:238125 32/117 (27%)
ANK repeat 896..923 CDD:293786 6/26 (23%)
Ank_2 898..989 CDD:289560 24/90 (27%)
ANK repeat 927..957 CDD:293786 5/29 (17%)
ANK repeat 959..991 CDD:293786 11/31 (35%)
ANK 989..>1049 CDD:238125 17/59 (29%)
ANK repeat 993..1023 CDD:293786 13/29 (45%)
Ank_4 995..1046 CDD:290365 16/50 (32%)
ANK 2321..2349 CDD:197603
ANK repeat 2323..2352 CDD:293786
Ank_2 2326..2419 CDD:289560
ANK 2350..2477 CDD:238125
ANK repeat 2354..2386 CDD:293786
ANK repeat 2390..2419 CDD:293786
Ank_2 2393..2486 CDD:289560
ANK repeat 2421..2452 CDD:293786
ANK repeat 2456..2486 CDD:293786
ANK 2457..2579 CDD:238125
Ank_2 2461..2552 CDD:289560
ANK repeat 2492..2521 CDD:293786
ANK 2519..2645 CDD:238125
ANK repeat 2523..2589 CDD:293786
Ank_2 2528..2622 CDD:289560
ANK repeat 2560..2587 CDD:293786
ANK repeat 2591..2622 CDD:293786
KH-I 3049..3110 CDD:238053
NfkbibNP_110494.2 ANKYR <57..148 CDD:223738 29/91 (32%)
ANK repeat 57..91 CDD:293786 7/33 (21%)
ANK 1 57..86 6/28 (21%)
ANK repeat 93..124 CDD:293786 10/31 (32%)
ANK 2 93..122 10/29 (34%)
ANK 3 126..155 8/28 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 153..192 12/49 (24%)
PHA03095 203..>298 CDD:222980 32/106 (30%)
ANK repeat 206..237 CDD:293786 11/30 (37%)
ANK 4 206..235 9/28 (32%)
ANK repeat 239..271 CDD:293786 13/31 (42%)
ANK 5 240..269 13/28 (46%)
ANK 6 273..302 7/29 (24%)
ANK repeat 273..298 CDD:293786 7/25 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 298..359 9/49 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166350278
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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