DRSC/TRiP Functional Genomics Resources

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Protein Alignment mask and ankrd52a

DIOPT Version :9

Sequence 1:NP_001247280.1 Gene:mask / 50070 FlyBaseID:FBgn0043884 Length:4010 Species:Drosophila melanogaster
Sequence 2:NP_001018164.1 Gene:ankrd52a / 553206 ZFINID:ZDB-GENE-050522-247 Length:1071 Species:Danio rerio


Alignment Length:656 Identity:184/656 - (28%)
Similarity:287/656 - (43%) Gaps:153/656 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   515 NIS---ALLEAAANEKAPVLRHATHAIDETKQALTKMRCASSPRDKNGFSRSLVAACTDNDVNTV 576
            |||   .|::|..|..|..::...|..||. .||.:.|  .:|         |.||....||:.:
Zfish     5 NISDQPPLVQAIFNRNADEVKLFLHKKDEV-NALDQER--RTP---------LHAAAWLGDVHIM 57

  Fly   577 KRLLCKG-NVNLND---------AAASTDDGESLLSMACSAG--------YYELAQVLLAMSAA- 622
            ..|:..| |||..|         ||||.:  |..:.:....|        |::....:.|.:.| 
Zfish    58 DLLISAGANVNAKDHVWLTPLHRAAASRN--ERAVGLLLRKGADVTARDKYWQTPLHIAAANRAT 120

  Fly   623 --------QVEDKGQKDST---PLMEAASAGHLDIVKLLLNHNADVNAHCATGNTPLMFACAGGQ 676
                    .|......|.|   ||..||.:|:.::||||||..|:::|.......|:.:|...|.
Zfish   121 RCVETLLPHVSSLNMADRTGRAPLHHAAQSGYQEMVKLLLNKGANLSASDKKDRQPIHWAAYLGH 185

  Fly   677 VDVVKVLLKHGANVEEQNENGHTPLMEAASAGHVEVAKVLLEHGAGINTHSNEFKESALTLACYK 741
            ::|||:|:..|::...:::.|:|||..||::|||:|.|.||.:||.|: ..|.|..:||.:|||.
Zfish   186 LEVVKLLVSQGSDKSCKDKRGYTPLHAAAASGHVDVVKYLLRNGAEID-EPNAFGNTALHVACYT 249

  Fly   742 GHLDMVRFLLQAGADQEHKTDEMHTALMEASMDGHVEVA-RLLLDSGAQVNMPTDSFESPLTLAA 805
            |...:...|:..||:........:|.|..|::..:..:. .||:::||.|||.:...:|||.:||
Zfish   250 GQEAVANELVNRGANVNQPNHRGYTPLHLAAVSTNGALCLELLVNNGADVNMQSKEGKSPLHMAA 314

  Fly   806 CGGHVELATLLIERGANIEEVNDEGYTPLMEAAREGHEEMVALLLSKGANINATTEETQETA--- 867
            ..|....:.:||:.|..|:.|:..|.|||..||:.|||.:::.|::.||          :||   
Zfish   315 IHGRFTRSQILIQNGGEIDCVDRYGNTPLHVAAKYGHELLISTLMTNGA----------DTARQG 369

  Fly   868 ------LTLA-------CC------GGFMEVAAFLIKE---GANLELGASTP-------LMEASQ 903
                  |.||       ||      |....:...:.||   .|..::  :||       |..|:.
Zfish   370 IHGMFPLHLAVLYGSSDCCRKLLSSGQLYSIVLSMSKEHVLSAGFDI--NTPDNFGRTCLHAAAS 432

  Fly   904 EGHTDLVSFLLKKKANVHAETQTGDTALTHACENGHTDAAGVLLSYGAELEHESEGGRTPLMKA- 967
            .|:.:.::.||...|:::.:.:.|.|.|.:|..||......||:..|||:......|.|||..: 
Zfish   433 GGNIECLNLLLSSGADMNKKDKFGRTPLHYAAANGRYQCVVVLVGAGAEVNERDRSGCTPLHYSA 497

  Fly   968 -----CRA-----------------GHLCTVKFLIQKGANVNKQTTSNDHTALSLACAGGHQSVV 1010
                 ||.                 ..|| |:.|:..||:.....|.. ::|:..|.|.|::..:
Zfish   498 ASTAFCRTDRPHASTHQNQEDGEKESFLC-VEHLLDNGADPCLCNTKG-YSAVHYAAAHGNKQNL 560

  Fly  1011 ELLLK------------NNADPFHKLKDNS-----TMLIE------------------ASKGGHT 1040
            ||||:            .:..|.|...::.     |:|||                  ||:.||:
Zfish   561 ELLLEMCFNTLGDKESNGSISPLHLAVESGHWECVTVLIESGVCVDVCDPVGRSVLYLASQRGHS 625

  Fly  1041 RVVELL 1046
            |.||||
Zfish   626 RCVELL 631

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
maskNP_001247280.1 ANK 555..684 CDD:238125 42/158 (27%)
Ank_2 564..659 CDD:289560 35/124 (28%)
ANK repeat 596..628 CDD:293786 6/48 (13%)
ANK 633..751 CDD:238125 46/120 (38%)
ANK repeat 633..661 CDD:293786 14/30 (47%)
Ank_2 635..724 CDD:289560 35/88 (40%)
ANK repeat 663..694 CDD:293786 8/30 (27%)
ANK repeat 696..724 CDD:293786 15/27 (56%)
Ank_5 716..771 CDD:290568 18/54 (33%)
ANK 726..850 CDD:238125 41/124 (33%)
ANK repeat 730..760 CDD:293786 10/29 (34%)
ANK repeat 765..794 CDD:293786 10/29 (34%)
Ank_2 768..859 CDD:289560 32/91 (35%)
ANK repeat 796..827 CDD:293786 10/30 (33%)
ANK repeat 829..858 CDD:293786 12/28 (43%)
ANK repeat 862..894 CDD:293786 11/56 (20%)
ANK 896..1014 CDD:238125 38/147 (26%)
ANK repeat 896..923 CDD:293786 8/33 (24%)
Ank_2 898..989 CDD:289560 29/113 (26%)
ANK repeat 927..957 CDD:293786 11/29 (38%)
ANK repeat 959..991 CDD:293786 12/54 (22%)
ANK 989..>1049 CDD:238125 24/93 (26%)
ANK repeat 993..1023 CDD:293786 9/41 (22%)
Ank_4 995..1046 CDD:290365 21/85 (25%)
ANK 2321..2349 CDD:197603
ANK repeat 2323..2352 CDD:293786
Ank_2 2326..2419 CDD:289560
ANK 2350..2477 CDD:238125
ANK repeat 2354..2386 CDD:293786
ANK repeat 2390..2419 CDD:293786
Ank_2 2393..2486 CDD:289560
ANK repeat 2421..2452 CDD:293786
ANK repeat 2456..2486 CDD:293786
ANK 2457..2579 CDD:238125
Ank_2 2461..2552 CDD:289560
ANK repeat 2492..2521 CDD:293786
ANK 2519..2645 CDD:238125
ANK repeat 2523..2589 CDD:293786
Ank_2 2528..2622 CDD:289560
ANK repeat 2560..2587 CDD:293786
ANK repeat 2591..2622 CDD:293786
KH-I 3049..3110 CDD:238053
ankrd52aNP_001018164.1 ANK repeat 852..883 CDD:293786
ANK 25 852..881
ANK repeat 885..917 CDD:293786
ANK 26 885..915
Ank_2 890..986 CDD:289560
ANK 27 919..951
ANK repeat 955..986 CDD:293786
ANK 28 955..984
ANK 5..127 CDD:238125 34/135 (25%)
ANK 1 7..36 8/29 (28%)
ANK repeat 11..38 CDD:293786 8/27 (30%)
Ank_2 12..104 CDD:289560 28/105 (27%)
ANK 2 40..69 11/39 (28%)
ANK repeat 42..71 CDD:293786 11/37 (30%)
ANK 68..193 CDD:238125 33/126 (26%)
ANK 3 73..102 6/30 (20%)
ANK repeat 76..104 CDD:293786 6/29 (21%)
ANK repeat 106..137 CDD:293786 4/30 (13%)
ANK 4 106..135 4/28 (14%)
Ank_2 111..203 CDD:289560 26/91 (29%)
ANK 134..259 CDD:238125 47/125 (38%)
ANK 5 139..168 13/28 (46%)
ANK repeat 140..170 CDD:293786 13/29 (45%)
ANK 6 172..201 8/28 (29%)
ANK repeat 176..203 CDD:293786 8/26 (31%)
Ank_2 177..269 CDD:289560 34/92 (37%)
ANK repeat 205..236 CDD:293786 16/31 (52%)
ANK 7 205..234 16/29 (55%)
ANKYR 207..410 CDD:223738 69/213 (32%)
ANK 233..359 CDD:238125 41/126 (33%)
ANK 8 238..267 10/28 (36%)
ANK repeat 238..266 CDD:293786 10/27 (37%)
ANK repeat 271..302 CDD:293786 9/30 (30%)
ANK 9 271..301 8/29 (28%)
ANK repeat 305..336 CDD:293786 10/30 (33%)
ANK 10 305..334 10/28 (36%)
ANK 333..476 CDD:238125 39/154 (25%)
ANK 11 338..367 13/38 (34%)
ANK repeat 338..363 CDD:293786 10/24 (42%)
ANK 12 371..400 6/28 (21%)
ANK repeat 375..420 CDD:293786 10/46 (22%)
ANK 417..564 CDD:238125 38/148 (26%)
ANK repeat 422..453 CDD:293786 6/30 (20%)
ANK 13 422..451 6/28 (21%)
Ank_2 427..541 CDD:289560 29/114 (25%)
ANK repeat 455..486 CDD:293786 11/30 (37%)
ANK 14 455..484 11/28 (39%)
ANK repeat 488..541 CDD:293786 12/53 (23%)
ANK 15 488..539 12/51 (24%)
ANK 16 543..573 8/30 (27%)
ANK repeat 544..576 CDD:293786 8/32 (25%)
Ank_2 549..636 CDD:289560 22/83 (27%)
ANK repeat 578..609 CDD:293786 6/30 (20%)
ANK 17 578..607 6/28 (21%)
ANK 581..702 CDD:238125 15/51 (29%)
ANK 18 611..640 9/21 (43%)
ANK repeat 611..636 CDD:293786 9/21 (43%)
ANK 19 645..674
ANK repeat 647..679 CDD:293786
ANK 649..768 CDD:238125
Ank_2 650..745 CDD:289560
ANK repeat 681..712 CDD:293786
ANK 20 681..710
ANK 709..837 CDD:238125
ANK repeat 714..745 CDD:293786
ANK 21 714..743
ANKYR 722..927 CDD:223738
ANK repeat 747..778 CDD:293786
ANK 22 747..776
ANK 23 784..814
ANK repeat 816..850 CDD:293786
ANK 24 816..845
ANK 847..976 CDD:238125
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1115202at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.920

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