DRSC/TRiP Functional Genomics Resources

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Protein Alignment mask and Ankrd28

DIOPT Version :9

Sequence 1:NP_001247280.1 Gene:mask / 50070 FlyBaseID:FBgn0043884 Length:4010 Species:Drosophila melanogaster
Sequence 2:XP_038950906.1 Gene:Ankrd28 / 306264 RGDID:1559931 Length:1053 Species:Rattus norvegicus


Alignment Length:1009 Identity:241/1009 - (23%)
Similarity:349/1009 - (34%) Gaps:352/1009 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   420 LAFLCLR--PDLLDDIPESDPDSCPHEGEVR----EDEDETEEESEDSDESEGEEEEEDEEEIDV 478
            :|||.||  |.|:..|...|||      |||    :.||                          
  Rat     1 MAFLKLRDQPSLVQAIFNGDPD------EVRALIFKKED-------------------------- 33

  Fly   479 LQDNDADDEEIDDEDEEEDAP-EVSSFLLDANNKRSSNISALLEAAANEK-----APVLRHATHA 537
                      ::.:|.|:..| ..:::|.||   ....:..|..|..|.|     .|:.|.....
  Rat    34 ----------VNFQDNEKRTPLHAAAYLGDA---EIIELLILSGARVNAKDSKWLTPLHRAVASC 85

  Fly   538 IDETKQALTKMRCASSPRDKNGFSRSLVAACTDNDVNTVKRLL-CKGNVNLNDAAASTDDGESLL 601
            .:|..|.|.|.....:.|||| :...|..|..:..|...:.|: ...|||::|.|     |.:.|
  Rat    86 SEEAVQILLKHSADVNARDKN-WQTPLHIAAANKAVKCAESLVPLLSNVNVSDRA-----GRTAL 144

  Fly   602 SMACSAGYYELAQVLLAMSA--------------------------------AQVEDKGQKDSTP 634
            ..|..:|:.|:.::||:..|                                |:|..|.:|..||
  Rat   145 HHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTP 209

  Fly   635 LMEAASAGHLDIVKLLLNHNADVNAHCATGNTPLMFACAGGQVDVVKVLLKHGANVEEQNENGHT 699
            |..|||:|.:.:||.||:...|:|...|.|||||..||..||..||..|:..||||.::||.|.|
  Rat   210 LHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNERGFT 274

  Fly   700 PLMEAASAGHVEVA-KVLLEHGAGINTHSNE-------------FKES----------------- 733
            ||..||::.|..:. ::|:.:||.:|..|.:             |..|                 
  Rat   275 PLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNG 339

  Fly   734 -----------------------------------ALTLACYKGHLDMVRFLLQAGADQEHKTDE 763
                                               .|.||...|..|..|.||.:|.|.:...|.
  Rat   340 NTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDF 404

  Fly   764 MHTALMEASMDGHVEVARLLLDSGAQVN------------------------------------- 791
            ..|.|..|:..|::|...|||::||..|                                     
  Rat   405 GRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDE 469

  Fly   792 ----------------------------------------------------------------- 791
                                                                             
  Rat   470 RGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLM 534

  Fly   792 ------MPTDSFE----SPLTLAACGGHVELATLLIERGANIEEVNDEGYTPLMEAAREGHEEMV 846
                  |.:||..    |||.|||..||.:...:|::...:::..|..|.|||..||.:||.|.|
  Rat   535 ETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECV 599

  Fly   847 ALLLSKGANINATTEETQETALTLACCGGFMEVAAFLI-----KEGANLELG-ASTPLMEASQEG 905
            .:|:::||:|.......:.|.:..|...|..|....||     :...:::.| ..||||.:...|
  Rat   600 DVLINQGASILVKDYVLKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNG 664

  Fly   906 HTDLVSFLLKKKANVHAETQTGDTALTHACENGHTDAAGVLLSYGAELEHESEGGRTPLMKACRA 970
            |||.|..||.|.|||.|:.:.|.|||......||.:....||.:||:.......||||:..:...
  Rat   665 HTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAAC 729

  Fly   971 GHLCTVKFLIQKGANVNKQ---TTSNDHTALSLACAGGHQSVVELLLK---------NNADPFH- 1022
            ||:..:..|:|...:|:..   ..::.:|||..||..||::.|||||:         |...|.| 
  Rat   730 GHIGVLGALLQSATSVDANPAIVDNHGYTALHWACYNGHETCVELLLEQDVFQKIDGNAFSPLHC 794

  Fly  1023 -KLKDN---STMLIEA----------SKG----------GHTRVVELLFRYPNISPTENAASANV 1063
             .:.||   :.|||:.          |||          .|...::||     :|......||:.
  Rat   795 AVINDNEGAAEMLIDTLGASIVNAPDSKGRTPLHAAAFTDHVECLQLL-----LSQNAQVNSADS 854

  Fly  1064 TQAAP---TSNQPGPNQMRQKIMKQQLQHQLQQLNAPPGLH---------------------ELS 1104
            |...|   .:.....|.:...:........||..:....||                     .|.
  Rat   855 TGKTPLMMAAENGQTNTVEMLVSSASADLTLQDKSKNTALHLACGKGHETSALLILEKITDRNLI 919

  Fly  1105 EAARASNQQHFHQQQFSSAGNGSSNIV--AMGTG 1136
            .|..|:.|...|    .:|.||.:.:|  .:|.|
  Rat   920 NATNAALQTPLH----VAARNGLTMVVQELLGKG 949

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
maskNP_001247280.1 ANK 555..684 CDD:238125 50/161 (31%)
Ank_2 564..659 CDD:289560 33/127 (26%)
ANK repeat 596..628 CDD:293786 10/63 (16%)
ANK 633..751 CDD:238125 52/183 (28%)
ANK repeat 633..661 CDD:293786 13/27 (48%)
Ank_2 635..724 CDD:289560 40/89 (45%)
ANK repeat 663..694 CDD:293786 16/30 (53%)
ANK repeat 696..724 CDD:293786 10/28 (36%)
Ank_5 716..771 CDD:290568 20/119 (17%)
ANK 726..850 CDD:238125 48/300 (16%)
ANK repeat 730..760 CDD:293786 12/81 (15%)
ANK repeat 765..794 CDD:293786 12/136 (9%)
Ank_2 768..859 CDD:289560 37/202 (18%)
ANK repeat 796..827 CDD:293786 10/34 (29%)
ANK repeat 829..858 CDD:293786 14/28 (50%)
ANK repeat 862..894 CDD:293786 7/37 (19%)
ANK 896..1014 CDD:238125 45/120 (38%)
ANK repeat 896..923 CDD:293786 15/26 (58%)
Ank_2 898..989 CDD:289560 33/90 (37%)
ANK repeat 927..957 CDD:293786 10/29 (34%)
ANK repeat 959..991 CDD:293786 9/34 (26%)
ANK 989..>1049 CDD:238125 26/96 (27%)
ANK repeat 993..1023 CDD:293786 15/40 (38%)
Ank_4 995..1046 CDD:290365 24/84 (29%)
ANK 2321..2349 CDD:197603
ANK repeat 2323..2352 CDD:293786
Ank_2 2326..2419 CDD:289560
ANK 2350..2477 CDD:238125
ANK repeat 2354..2386 CDD:293786
ANK repeat 2390..2419 CDD:293786
Ank_2 2393..2486 CDD:289560
ANK repeat 2421..2452 CDD:293786
ANK repeat 2456..2486 CDD:293786
ANK 2457..2579 CDD:238125
Ank_2 2461..2552 CDD:289560
ANK repeat 2492..2521 CDD:293786
ANK 2519..2645 CDD:238125
ANK repeat 2523..2589 CDD:293786
Ank_2 2528..2622 CDD:289560
ANK repeat 2560..2587 CDD:293786
ANK repeat 2591..2622 CDD:293786
KH-I 3049..3110 CDD:238053
Ankrd28XP_038950906.1 ANK repeat 12..38 CDD:293786 10/67 (15%)
PHA03095 22..>310 CDD:222980 91/338 (27%)
ANK repeat 40..71 CDD:293786 8/33 (24%)
ANK repeat 76..104 CDD:293786 6/27 (22%)
ANK repeat 106..137 CDD:293786 8/31 (26%)
ANK repeat 140..170 CDD:293786 8/29 (28%)
ANK repeat 172..203 CDD:293786 2/30 (7%)
PHA03095 186..>454 CDD:222980 72/267 (27%)
ANK repeat 205..236 CDD:293786 14/30 (47%)
ANK repeat 238..269 CDD:293786 16/30 (53%)
ANK repeat 271..302 CDD:293786 11/30 (37%)
ANK repeat 305..336 CDD:293786 2/30 (7%)
ANK repeat 338..363 CDD:293786 0/24 (0%)
ANK repeat 371..402 CDD:293786 10/30 (33%)
ANK repeat 404..435 CDD:293786 11/30 (37%)
ANK repeat 437..468 CDD:293786 0/30 (0%)
ANK repeat 470..502 CDD:293786 0/31 (0%)
Ank_2 475..580 CDD:403870 12/104 (12%)
ANK repeat 552..580 CDD:293786 9/27 (33%)
PHA02874 554..>863 CDD:165205 95/313 (30%)
ANK repeat 582..613 CDD:293786 14/30 (47%)
ANK repeat 618..650 CDD:293786 6/31 (19%)
ANK repeat 652..683 CDD:293786 16/30 (53%)
ANK repeat 685..716 CDD:293786 10/30 (33%)
ANK repeat 718..747 CDD:293786 9/28 (32%)
ANK repeat 755..820 CDD:293786 20/64 (31%)
ANK repeat 823..853 CDD:293786 6/34 (18%)
Ank_2 827..920 CDD:403870 14/97 (14%)
ANK repeat 855..887 CDD:293786 4/31 (13%)
ANK repeat 889..920 CDD:293786 3/30 (10%)
ANK repeat 925..956 CDD:293786 8/29 (28%)
Ank 927..957 CDD:394980 8/27 (30%)
Ank_2 930..1006 CDD:423045 7/24 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1115202at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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