Protein Alignment mask and Nfkbia

DIOPT Version :10

• Sequence 1: NP_001247280.1
• Gene: mask / 50070
• FlyBaseID: FBgn0043884
• Length: 4010
• Species: Drosophila melanogaster
• Sequence 2: NP_035037.2
• Gene: Nfkbia / 18035
• MGIID: 104741
• Length: 314
• Species: Mus musculus
• Alignment Length: 243
• Identity: 65/243 - (26%)
• Similarity: 94/243 - (38%)
• Gaps: 63/243 - (25%)

  Fly   594 TDDGESLLSMACSAGYYELAQVLLAMSAAQVEDKGQKDSTPL-MEAASAGHLDIVKLLLNHNADV 657
            |:||:|.|.:|...                 |:|      || ||.......|:..|...:|..
Mouse    71 TEDGDSFLHLAIIH-----------------EEK------PLTMEVIGQVKGDLAFLNFQNNLQ- 111

  Fly   658 NAHCATGNTPLMFACAGGQVDVVKVLLKHGANVEEQNENGHTPLMEAASAGHVEVAKVLLEHGAG 722
                   .|||..|....|..:.:.|||.|.:.|.::..|:|||..|...|.:....|
Mouse   112 -------QTPLHLAVITNQPGIAEALLKAGCDPELRDFRGNTPLHLACEQGCLASVAV------- 162

  Fly   723 INTHSNEFKESALTLACYKGHLDMVRFLLQAGADQEHKTDEMHTALMEASMDGHVEVARLLLDSG 787
                        ||..|...||..|   |||      .....||.|..||:.|::.:...|:..|
Mouse   163 ------------LTQTCTPQHLHSV---LQA------TNYNGHTCLHLASIHGYLAIVEHLVTLG 206

  Fly   788 AQVNM--PTDSFESPLTLAACGGHVELATLLIERGANIEEVNDEGYTP 833
            |.||.  |.:. .:.|.||....:.:|.:||::.||::..|..:||:|
Mouse   207 ADVNAQEPCNG-RTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSP 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mask	NP_001247280.1	ANKYR	584..858	CDD:440430	65/243 (27%)
		ANK repeat	596..628	CDD:293786	6/31 (19%)
		ANK repeat	633..661	CDD:293786	7/28 (25%)
		ANK repeat	663..694	CDD:293786	10/30 (33%)
		ANK repeat	696..724	CDD:293786	7/27 (26%)
		ANK repeat	730..760	CDD:293786	9/29 (31%)
		ANKYR	744..1062	CDD:440430	29/92 (32%)
		ANK repeat	765..794	CDD:293786	11/30 (37%)
		ANK repeat	796..827	CDD:293786	8/30 (27%)
		ANK repeat	829..858	CDD:293786	3/5 (60%)
		ANK repeat	862..894	CDD:293786
		ANK repeat	896..923	CDD:293786
		ANK repeat	927..957	CDD:293786
		ANK repeat	959..991	CDD:293786
		ANK repeat	993..1023	CDD:293786
		ANK	2321..2349	CDD:197603
		ANK repeat	2323..2352	CDD:293786
		ANKYR	2336..2623	CDD:440430
		ANK repeat	2354..2386	CDD:293786
		ANK repeat	2390..2419	CDD:293786
		ANK repeat	2421..2452	CDD:293786
		ANK repeat	2456..2486	CDD:293786
		ANK repeat	2492..2521	CDD:293786
		ANK repeat	2523..2589	CDD:293786
		ANK repeat	2560..2587	CDD:293786
		ANK repeat	2591..2622	CDD:293786
		KH-I_MASK	3047..3116	CDD:411832
Nfkbia	NP_035037.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..40
		Destruction motif. /evidence=ECO:0000250|UniProtKB:P25963	30..36
		ANKYR	34..>256	CDD:440430	65/243 (27%)
		Nuclear export signal. /evidence=ECO:0000250|UniProtKB:P25963	45..54
		ANK repeat	73..108	CDD:293786	13/57 (23%)
		ANK 1	73..103		12/52 (23%)
		ANK repeat	110..141	CDD:293786	10/38 (26%)
		ANK 2	110..139		9/36 (25%)
		Nuclear import signal. /evidence=ECO:0000250|UniProtKB:P25963	110..120		4/17 (24%)
		ANK repeat	143..180	CDD:293786	16/64 (25%)
		ANK 3	143..172		10/47 (21%)
		ANK repeat	182..213	CDD:293786	11/30 (37%)
		ANK 4	182..211		10/28 (36%)
		ANK repeat	216..246	CDD:293786	8/30 (27%)
		ANK 5	216..245		8/29 (28%)