DRSC/TRiP Functional Genomics Resources

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Protein Alignment mask and Nfkbia

DIOPT Version :9

Sequence 1:NP_001247280.1 Gene:mask / 50070 FlyBaseID:FBgn0043884 Length:4010 Species:Drosophila melanogaster
Sequence 2:NP_035037.2 Gene:Nfkbia / 18035 MGIID:104741 Length:314 Species:Mus musculus


Alignment Length:243 Identity:65/243 - (26%)
Similarity:94/243 - (38%) Gaps:63/243 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   594 TDDGESLLSMACSAGYYELAQVLLAMSAAQVEDKGQKDSTPL-MEAASAGHLDIVKLLLNHNADV 657
            |:||:|.|.:|...                 |:|      || ||.......|:..|...:|.. 
Mouse    71 TEDGDSFLHLAIIH-----------------EEK------PLTMEVIGQVKGDLAFLNFQNNLQ- 111

  Fly   658 NAHCATGNTPLMFACAGGQVDVVKVLLKHGANVEEQNENGHTPLMEAASAGHVEVAKVLLEHGAG 722
                   .|||..|....|..:.:.|||.|.:.|.::..|:|||..|...|.:....|       
Mouse   112 -------QTPLHLAVITNQPGIAEALLKAGCDPELRDFRGNTPLHLACEQGCLASVAV------- 162

  Fly   723 INTHSNEFKESALTLACYKGHLDMVRFLLQAGADQEHKTDEMHTALMEASMDGHVEVARLLLDSG 787
                        ||..|...||..|   |||      .....||.|..||:.|::.:...|:..|
Mouse   163 ------------LTQTCTPQHLHSV---LQA------TNYNGHTCLHLASIHGYLAIVEHLVTLG 206

  Fly   788 AQVNM--PTDSFESPLTLAACGGHVELATLLIERGANIEEVNDEGYTP 833
            |.||.  |.:. .:.|.||....:.:|.:||::.||::..|..:||:|
Mouse   207 ADVNAQEPCNG-RTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSP 253

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
maskNP_001247280.1 ANK 555..684 CDD:238125 20/90 (22%)
Ank_2 564..659 CDD:289560 15/65 (23%)
ANK repeat 596..628 CDD:293786 6/31 (19%)
ANK 633..751 CDD:238125 30/118 (25%)
ANK repeat 633..661 CDD:293786 7/28 (25%)
Ank_2 635..724 CDD:289560 23/89 (26%)
ANK repeat 663..694 CDD:293786 10/30 (33%)
ANK repeat 696..724 CDD:293786 7/27 (26%)
Ank_5 716..771 CDD:290568 12/54 (22%)
ANK 726..850 CDD:238125 33/110 (30%)
ANK repeat 730..760 CDD:293786 9/29 (31%)
ANK repeat 765..794 CDD:293786 11/30 (37%)
Ank_2 768..859 CDD:289560 22/68 (32%)
ANK repeat 796..827 CDD:293786 8/30 (27%)
ANK repeat 829..858 CDD:293786 3/5 (60%)
ANK repeat 862..894 CDD:293786
ANK 896..1014 CDD:238125
ANK repeat 896..923 CDD:293786
Ank_2 898..989 CDD:289560
ANK repeat 927..957 CDD:293786
ANK repeat 959..991 CDD:293786
ANK 989..>1049 CDD:238125
ANK repeat 993..1023 CDD:293786
Ank_4 995..1046 CDD:290365
ANK 2321..2349 CDD:197603
ANK repeat 2323..2352 CDD:293786
Ank_2 2326..2419 CDD:289560
ANK 2350..2477 CDD:238125
ANK repeat 2354..2386 CDD:293786
ANK repeat 2390..2419 CDD:293786
Ank_2 2393..2486 CDD:289560
ANK repeat 2421..2452 CDD:293786
ANK repeat 2456..2486 CDD:293786
ANK 2457..2579 CDD:238125
Ank_2 2461..2552 CDD:289560
ANK repeat 2492..2521 CDD:293786
ANK 2519..2645 CDD:238125
ANK repeat 2523..2589 CDD:293786
Ank_2 2528..2622 CDD:289560
ANK repeat 2560..2587 CDD:293786
ANK repeat 2591..2622 CDD:293786
KH-I 3049..3110 CDD:238053
NfkbiaNP_035037.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..40
Ank_2 <26..>151 CDD:330894 29/110 (26%)
Destruction motif 30..36
Nuclear export signal. /evidence=ECO:0000250 45..54
ANK repeat 73..108 CDD:293786 13/57 (23%)
ANK 1 73..103 12/52 (23%)
ANK 105..237 CDD:238125 44/168 (26%)
ANK repeat 110..141 CDD:293786 10/38 (26%)
ANK 2 110..139 9/36 (25%)
Nuclear import signal. /evidence=ECO:0000250 110..120 4/17 (24%)
ANK repeat 143..180 CDD:293786 16/64 (25%)
ANK 3 143..172 10/47 (21%)
ANK repeat 182..213 CDD:293786 11/30 (37%)
ANK 4 182..211 10/28 (36%)
ANK repeat 216..246 CDD:293786 8/30 (27%)
ANK 5 216..245 8/29 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167846754
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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