DRSC/TRiP Functional Genomics Resources

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Protein Alignment mask and ANKRD22

DIOPT Version :9

Sequence 1:NP_001247280.1 Gene:mask / 50070 FlyBaseID:FBgn0043884 Length:4010 Species:Drosophila melanogaster
Sequence 2:NP_653191.2 Gene:ANKRD22 / 118932 HGNCID:28321 Length:191 Species:Homo sapiens


Alignment Length:182 Identity:55/182 - (30%)
Similarity:82/182 - (45%) Gaps:35/182 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   884 IKEG---ANLELG--ASTPLMEASQEGHTDLVSFLLKKKANVHAETQTGDTALTHACENGHT--D 941
            :||.   ||::.|  ..|||:.|.:.||..:|||||::.|||:.:.|...|.|.:|.:...|  |
Human    25 VKEDSSYANVQDGFNGDTPLICACRRGHVRIVSFLLRRNANVNLKNQKERTCLHYAVKKKFTFID 89

  Fly   942 AAGVLLSYGAELEHESEGGRTPLMKACRAGHL----------CTVKFLIQKGANVNKQTTSNDHT 996
            ...::|                ||.....|:.          ..|:.|:..|..|| .|.....|
Human    90 YLLIIL----------------LMPVLLIGYFLMVSKTKQNEALVRMLLDAGVEVN-ATDCYGCT 137

  Fly   997 ALSLACAGGHQSVVELLLKNNADPFHKLKDNSTMLIEASKGGHTRVVELLFR 1048
            ||..||...:||::.|||:..|||..|.|...:.|..|.:...:: :||:.|
Human   138 ALHYACEMKNQSLIPLLLEARADPTIKNKHGESSLDIARRLKFSQ-IELMLR 188

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
maskNP_001247280.1 ANK 555..684 CDD:238125
Ank_2 564..659 CDD:289560
ANK repeat 596..628 CDD:293786
ANK 633..751 CDD:238125
ANK repeat 633..661 CDD:293786
Ank_2 635..724 CDD:289560
ANK repeat 663..694 CDD:293786
ANK repeat 696..724 CDD:293786
Ank_5 716..771 CDD:290568
ANK 726..850 CDD:238125
ANK repeat 730..760 CDD:293786
ANK repeat 765..794 CDD:293786
Ank_2 768..859 CDD:289560
ANK repeat 796..827 CDD:293786
ANK repeat 829..858 CDD:293786
ANK repeat 862..894 CDD:293786 5/14 (36%)
ANK 896..1014 CDD:238125 38/129 (29%)
ANK repeat 896..923 CDD:293786 14/26 (54%)
Ank_2 898..989 CDD:289560 27/102 (26%)
ANK repeat 927..957 CDD:293786 6/31 (19%)
ANK repeat 959..991 CDD:293786 8/41 (20%)
ANK 989..>1049 CDD:238125 21/60 (35%)
ANK repeat 993..1023 CDD:293786 13/29 (45%)
Ank_4 995..1046 CDD:290365 18/50 (36%)
ANK 2321..2349 CDD:197603
ANK repeat 2323..2352 CDD:293786
Ank_2 2326..2419 CDD:289560
ANK 2350..2477 CDD:238125
ANK repeat 2354..2386 CDD:293786
ANK repeat 2390..2419 CDD:293786
Ank_2 2393..2486 CDD:289560
ANK repeat 2421..2452 CDD:293786
ANK repeat 2456..2486 CDD:293786
ANK 2457..2579 CDD:238125
Ank_2 2461..2552 CDD:289560
ANK repeat 2492..2521 CDD:293786
ANK 2519..2645 CDD:238125
ANK repeat 2523..2589 CDD:293786
Ank_2 2528..2622 CDD:289560
ANK repeat 2560..2587 CDD:293786
ANK repeat 2591..2622 CDD:293786
KH-I 3049..3110 CDD:238053
ANKRD22NP_653191.2 Ank_4 5..60 CDD:372654 14/34 (41%)
Ank_2 <39..>175 CDD:423045 46/152 (30%)
ANK repeat 39..70 CDD:293786 14/30 (47%)
ANK 1 39..68 14/28 (50%)
ANK repeat 72..132 CDD:293786 14/76 (18%)
ANK 2 72..100 8/43 (19%)
ANK 3 101..130 6/29 (21%)
ANK repeat 134..165 CDD:293786 13/30 (43%)
ANK 4 134..163 13/28 (46%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165156349
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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