Protein Alignment Hsp70Bbb and ECM10

DIOPT Version :9

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_010884.1
• Gene: ECM10 / 856682
• SGDID: S000000756
• Length: 644
• Species: Saccharomyces cerevisiae
• Alignment Length: 618
• Identity: 304/618 - (49%)
• Similarity: 420/618 - (67%)
• Gaps: 29/618 - (4%)

  Fly     4 IGIDLGTTYSCVGVYQHGKV-EIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFD 66
            ||||||||.|.|.:.: ||| .||.|.:|:|||||.|||| |.|||:|:|||.|..:|..||:|.
Yeast    30 IGIDLGTTNSAVAIME-GKVPRIIENAEGSRTTPSVVAFTKDGERLVGEPAKRQSVINSENTLFA 93

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVV--SDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAE 129
            .||||||:::|.::..|:...|||:|  |:|     ....:..::.::|.:|...:|.|||||||
Yeast    94 TKRLIGRRFEDAEVQRDINQVPFKIVKHSNG-----DAWVEARNRTYSPAQIGGFILNKMKETAE 153

  Fly   130 AYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKDERNVLI 194
            |||.:|:.:||:||||||||:|||||||||.|.||||||::||||||||||||||:  :.:.:.:
Yeast   154 AYLAKSVKNAVVTVPAYFNDAQRQATKDAGQIIGLNVLRVVNEPTAAALAYGLDKS--EPKVIAV 216

  Fly   195 FDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALR 259
            |||||||||:|||.||.| :|||:||.|||||||||||..|:..:...||::...||.::..|::
Yeast   217 FDLGGGTFDISILDIDNG-IFEVKSTNGDTHLGGEDFDIYLLQEIISHFKKETGIDLSNDRMAVQ 280

  Fly   260 RLRTAAERAKRTLSS--STEATIE-IDALFEG-QDFYTKVSRARFEELCADLFRNTLQPVEKALN 320
            |:|.|||:||..|||  |||..:. |.|...| :......||.:.|.:.|.|...|:.||:|||.
Yeast   281 RIREAAEKAKIELSSTLSTEINLPFITADAAGPKHIRMPFSRVQLENITAPLIDRTVDPVKKALK 345

  Fly   321 DAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGK 385
            ||::....|.|::||||.:|:|||...:::.| ||:.:.::|||||||.|||:|||:|||:
Yeast   346 DARITASDISDVLLVGGMSRMPKVADTVKKLF-GKDASKAVNPDEAVALGAAIQAAVLSGE---- 405

  Fly   386 IQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKD 450
            :.||||:||.||||||||.|||.||||.||..||.|:::.|||.:..|..|.::|::|||.:.||
Yeast   406 VTDVLLLDVTPLSLGIETLGGVFTKLIPRNSTIPNKKSQIFSTAASGQTSVEVKVFQGERELVKD 470

  Fly   451 NNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDR 515
            |..:|.|.|:||||||:|.||||||||:|||||:|||||::::.|..:||:....| ||..||||
Yeast   471 NKLIGNFTLAGIPPAPKGTPQIEVTFDIDANGIINVSAKDLASHKDSSITVAGASG-LSDTEIDR 534

  Fly   516 MVNEAEKYADEDEKHRQRITSRNALESYVFNVKQSVEQAPAGKLDEADKNSVLDKCNETIRWLDS 580
            ||||||:|.::|...|..|.:.|..:....:.:.|:::. .||||:.|...:.|:.: ::|.|.|
Yeast   535 MVNEAERYKNQDRARRNAIETANKADQLANDTENSIKEF-EGKLDKTDSQRLKDQIS-SLRELVS 597

  Fly   581 NTTAEKEEFDH----KMEELTRHCSPIMTKMHQ 609
            .:.|..|..|.    |::.|......:..::::
Yeast   598 RSQAGDEVNDDDVGTKIDNLRTSSMKLFEQLYK 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	304/618 (49%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	199/382 (52%)
ECM10	NP_010884.1	dnaK	29..644	CDD:234715	304/618 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810