Protein Alignment Hsp70Bbb and hspa1b

DIOPT Version :10

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001093532.1
• Gene: hspa1b / 798846
• ZFINID: ZDB-GENE-060503-867
• Length: 639
• Species: Danio rerio
• Alignment Length: 640
• Identity: 470/640 - (73%)
• Similarity: 542/640 - (84%)
• Gaps: 7/640 - (1%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            :||||||||||||||:|||||||||||||||||||||||||:||||||.|||||||||.||:|||
Zfish     6 SIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTIFDA 70

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            |||||||:||..:..|||.|||||:|:.||||:.||||||:|.|.|||||||||.||:|.|||||
Zfish    71 KRLIGRKFDDQVVQSDMKLWPFKVISEDGKPKVQVEYKGENKTFYPEEISSMVLVKMREIAEAYL 135

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKDERNVLIFDL 197
            |..:.:|||||||||||||||||||||.|||||||||||||||||:||||||..|.|||||||||
Zfish   136 GHRVNNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGRKGERNVLIFDL 200

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLR 262
            ||||||||||||::| :|||::|||||||||||||||:|.|..||||||:|||:..|.||:||||
Zfish   201 GGGTFDVSILTIEDG-IFEVKATAGDTHLGGEDFDNRMVKHFVEEFKRKHKKDISQNKRAVRRLR 264

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            ||.||||||||||::|:||||:||||.||||.::|||||||.|:|||.||.||||||.||||||.
Zfish   265 TACERAKRTLSSSSQASIEIDSLFEGIDFYTSITRARFEELNAELFRGTLDPVEKALRDAKMDKS 329

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            ||.|||||||||||||:|.|||:||:|::||.|||||||||||||||||||.||.|..:||:||:
Zfish   330 QIQDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDTSENVQDLLLL 394

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTF 457
            |||||||||||||||||.||:||..||.|||:.|||||||||||.|||:|||||||||||.||.|
Zfish   395 DVAPLSLGIETAGGVMTALIKRNTTIPTKQTQIFSTYSDNQPGVLIQVFEGERAMTKDNNLLGKF 459

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            ||:|||||||||||||||||:||||||||||.:.||||...|||.|||||||:.:|:|||.:|||
Zfish   460 DLTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDKGRLSKEDIERMVQDAEK 524

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQSVE-QAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEK 586
            |..|||..|::|.::||||||.|::|.:|| :...||:.|.||..::|||.|.:.||::|..|||
Zfish   525 YKAEDEVQREKIAAKNALESYAFSMKNTVEDENLRGKISEQDKKKIIDKCTEVVSWLENNQLAEK 589

  Fly   587 EEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQAGGFGGYSGPTVEEVD 641
            ||::|..:||...|:||:::::|.||..|||    ||.||..... .|||:||||
Zfish   590 EEYEHHQKELESVCNPIISRLYQGGAPPAGG----CGFQAQPESS-QGPTIEEVD 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	468/638 (73%)
hspa1b	NP_001093532.1	PTZ00009	1..639	CDD:240227	468/638 (73%)